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HomeProduct name listMETHYL ACETIMIDATE HYDROCHLORIDE

METHYL ACETIMIDATE HYDROCHLORIDE

  • CAS NO.:14777-27-6
  • Empirical Formula: C3H8ClNO
  • Molecular Weight: 109.55
  • MDL number: MFCD00012571
  • EINECS: 238-843-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:08:52
METHYL ACETIMIDATE HYDROCHLORIDE Structural

What is METHYL ACETIMIDATE HYDROCHLORIDE?

Chemical properties

White to yellow powder

The Uses of METHYL ACETIMIDATE HYDROCHLORIDE

Methyl acetimidate hydrochloride has been used in pre-crystallization chemical modification of lysine residues.

General Description

Methyl acetimidate hydrochloride is an inhibitor of N-methylation of phosphatidylethanolamine. It also prevents the stimulation of purified cardiac sarcolemmal vesicles Ca2+-pump activities.

Purification Methods

Crystallise the imidate from methanol by adding dry ether to a ratio of 1:1 and cooling at 0o. Filter off the crystals in a cold room, wash them with methanol/ether (1:2), then dry in a vacuum. [Hunter & Ludwig J Am Chem Soc 84 3491 1962.] The free base has b 90-91o/765mm, d 0.867, n 1.403. [Hunter & Ludwig Methods Enzymol 25 585 1973, Beilstein 2 IV 181.]

Properties of METHYL ACETIMIDATE HYDROCHLORIDE

Melting point: 105 °C (dec.)(lit.)
storage temp.  2-8°C
BRN  3671581
EPA Substance Registry System Ethanimidic acid, methyl ester, hydrochloride (14777-27-6)

Safety information for METHYL ACETIMIDATE HYDROCHLORIDE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for METHYL ACETIMIDATE HYDROCHLORIDE

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