METHYL ACETIMIDATE HYDROCHLORIDE
- CAS NO.:14777-27-6
- Empirical Formula: C3H8ClNO
- Molecular Weight: 109.55
- MDL number: MFCD00012571
- EINECS: 238-843-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:08:52
What is METHYL ACETIMIDATE HYDROCHLORIDE?
Chemical properties
White to yellow powder
The Uses of METHYL ACETIMIDATE HYDROCHLORIDE
Methyl acetimidate hydrochloride has been used in pre-crystallization chemical modification of lysine residues.
General Description
Methyl acetimidate hydrochloride is an inhibitor of N-methylation of phosphatidylethanolamine. It also prevents the stimulation of purified cardiac sarcolemmal vesicles Ca2+-pump activities.
Purification Methods
Crystallise the imidate from methanol by adding dry ether to a ratio of 1:1 and cooling at 0o. Filter off the crystals in a cold room, wash them with methanol/ether (1:2), then dry in a vacuum. [Hunter & Ludwig J Am Chem Soc 84 3491 1962.] The free base has b 90-91o/765mm, d 0.867, n 1.403. [Hunter & Ludwig Methods Enzymol 25 585 1973, Beilstein 2 IV 181.]
Properties of METHYL ACETIMIDATE HYDROCHLORIDE
Melting point: | 105 °C (dec.)(lit.) |
storage temp. | 2-8°C |
BRN | 3671581 |
EPA Substance Registry System | Ethanimidic acid, methyl ester, hydrochloride (14777-27-6) |
Safety information for METHYL ACETIMIDATE HYDROCHLORIDE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for METHYL ACETIMIDATE HYDROCHLORIDE
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
Carbamic acid, acetyl-, 1,1-dimethylethyl ester (9CI)
Acetyl-D-2-aminobutyric acid
METHYL ACETIMIDATE HYDROCHLORIDE
METHYL BENZIMIDATE HYDROCHLORIDE
DIMETHYL 3,3'-DITHIO-BIS(PROPIONIMIDATE) DIHYDROCHLORIDE
ETHYL 4-HYDROXYBENZIMIDATE HYDROCHLORIDE
METHYL 2,2,2-TRICHLOROACETIMIDATE
DIETHYL MALONIMIDATE DIHYDROCHLORIDE
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