METHYL ACETIMIDATE HYDROCHLORIDE
- CAS NO.：14777-27-6
- Empirical Formula: C3H8ClNO
- Molecular Weight: 109.55
- MDL number: MFCD00012571
- EINECS: 238-843-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2022-12-30 16:20:48
What is METHYL ACETIMIDATE HYDROCHLORIDE?
Chemical properties
White to yellow powder
The Uses of METHYL ACETIMIDATE HYDROCHLORIDE
Methyl acetimidate hydrochloride has been used in pre-crystallization chemical modification of lysine residues.
General Description
Methyl acetimidate hydrochloride is an inhibitor of N-methylation of phosphatidylethanolamine. It also prevents the stimulation of purified cardiac sarcolemmal vesicles Ca2+-pump activities.
Purification Methods
Crystallise the imidate from methanol by adding dry ether to a ratio of 1:1 and cooling at 0o. Filter off the crystals in a cold room, wash them with methanol/ether (1:2), then dry in a vacuum. [Hunter & Ludwig J Am Chem Soc 84 3491 1962.] The free base has b 90-91o/765mm, d 0.867, n 1.403. [Hunter & Ludwig Methods Enzymol 25 585 1973, Beilstein 2 IV 181.]
Properties of METHYL ACETIMIDATE HYDROCHLORIDE
| Melting point: | 105 °C (dec.)(lit.) |
| storage temp. | 2-8°C |
| BRN | 3671581 |
| EPA Substance Registry System | Ethanimidic acid, methyl ester, hydrochloride (14777-27-6) |
Safety information for METHYL ACETIMIDATE HYDROCHLORIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for METHYL ACETIMIDATE HYDROCHLORIDE
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