methyl 6-(bromomethyl)nicotinate
- CAS NO.：131803-48-0
- Empirical Formula: C8H8BrNO2
- Molecular Weight: 230.06
- MDL number: MFCD10566280
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-24 18:11:54
What is methyl 6-(bromomethyl)nicotinate?
The Uses of methyl 6-(bromomethyl)nicotinate
methyl 6-(bromomethyl)nicotinate is an organic reagent mainly used in chemical and scientific laboratory research.
Synthesis
methyl 6-(bromomethyl)nicotinate is synthesised using methyl 6-methylnicotinate as a raw material by chemical reaction. The specific synthesis steps are as follows:
0.471 g (1.0 equivalent) of N-bromosuccinimide and 64 mg (0.1 equivalent) of benzoyl peroxide are added to a solution of 0.4 g of the product obtained in the preceding Stage 1 in 15 ml of carbon tetrachloride. The solution is brought to reflux for 6 hours, then filtered and evaporated under reduced pressure. The residue is purified by chromatography on silica gel (dichloromethane/ethyl acetate: 95/5) to produce 0.262 g of the expected product. [ Yield: 43percent MS: MH+ 231].
Properties of methyl 6-(bromomethyl)nicotinate
| Boiling point: | 284.9±30.0℃ (760 Torr) |
| Density | 1.533±0.06 g/cm3 (20 ºC 760 Torr) |
| Flash point: | 126.1±24.6℃ |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 1.40±0.22(Predicted) |
| form | solid |
| color | OFF WHITE |
Safety information for methyl 6-(bromomethyl)nicotinate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for methyl 6-(bromomethyl)nicotinate
methyl 6-(bromomethyl)nicotinate manufacturer
BTC Pharmaceuticals Technology India
Andhra Pradesh
product: Methyl 6-(Bromomethyl)Nicotinate,Cas No:131803-48-0
New Products
4,4-Difluoropiperidine hydrochloride tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Indole Methyl Resin N-Isopropylurea N,N-Dicyclohexylcarbodiimide(DCC) MELDRUMS ACID 5-METHYLISOXAZOLE-4-CARBOXYLIC ACID Magnessium Bis glycinate Zinc ascorbate 1-bromo-2-butyne 2-acetamidophenol 9(10H)-anthracenone Erythrosin B, 4-Piperidinopiperidine 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 2,4-dihydroxybenzaldehyde 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile Methyl 2-methylquinoline-6-carboxylate 2,6-dichloro-4-nitropyridine 4-Bromo-2-chlorobenzonitrile 2-(benzylamino)acetic acid hydrochloride 4-(tert-Butoxycarbonylamino)but- 2-ynoic acid 3,4-dihydro-2H-benzo[b][1,4]dioxepine 1-Phenyl-1-cycloprppanecarboxylicacidRelated products of tetrahydrofuran
You may like
-
Methyl 6-(bromomethyl)nicotinate 95% CAS 131803-48-0View Details
131803-48-0 -
Methyl 6-(Bromomethyl)Nicotinate,Cas No:131803-48-0View Details
131803-48-0 -
3-(4-amino-1-oxoisoindolin-2-yl)-1-methylpiperidine-2,6-dione 98%View Details
-
614-19-7 98%View Details
614-19-7 -
20677-73-0 (2,2-diethoxyethyl)methylamine 98%View Details
20677-73-0 -
3-(4-(hydroxyamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione 98%View Details
-
57381-49-4 2-bromo-4-chlorobenzonitrile 98%View Details
57381-49-4 -
4,6-dichloropyrimidine-5-carbaldehyde 98%View Details
5305-40-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.