Methyl 4-hydroxycinnamate
- CAS NO.：3943-97-3
- Empirical Formula: C10H10O3
- Molecular Weight: 178.18
- MDL number: MFCD24849120
- EINECS: 223-531-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-20 11:41:24
What is Methyl 4-hydroxycinnamate?
Description
Methyl 4-hydroxycinnamate is an atifungal agent and a cinnamic acid derivative used in structure-antifungal activity relationship studies against Aspergillus flavus, Aspergillus terreus, and Aspergillus niger.
Occurrence
Methyl 4-hydroxycinnamate isolated from the herbs of Piper longum, Alpinia blepharocalyx, and Grevillea robusta.
The Uses of Methyl 4-hydroxycinnamate
3-(4-Hydroxyphenyl)-2-propenoic Acid Methyl Ester is used in the synthesis of AB3 and constitutional isomeric AB2 phenylpropyl ether-based supramolecular dendrimers. Also used in the synthesis of potent antagonists of leukotrines.
Definition
ChEBI: 4-coumaric acid methyl ester is a cinnamate ester that is the methyl ester of 4-coumaric acid. It has a role as a melanin synthesis inhibitor, a fungal metabolite, an anti-inflammatory agent, an antifungal agent and a plant metabolite. It is a cinnamate ester, a member of phenols and a methyl ester. It derives from a 4-coumaric acid.
Synthesis Reference(s)
Chemical and Pharmaceutical Bulletin, 28, p. 3662, 1980 DOI: 10.1248/cpb.28.3662
Properties of Methyl 4-hydroxycinnamate
| Melting point: | 144-145° |
| Boiling point: | 306.6±17.0 °C(Predicted) |
| Density | 1?+-.0.06 g/cm3(Predicted) |
| vapor pressure | 0.056Pa at 25℃ |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 8.82±0.13(Predicted) |
| color | White |
| Water Solubility | 5.332g/L at 25℃ |
| CAS DataBase Reference | 3943-97-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Propenoic acid, 3-(4-hydroxyphenyl)-, methyl ester(3943-97-3) |
Safety information for Methyl 4-hydroxycinnamate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Methyl 4-hydroxycinnamate
New Products
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