Methyl 2-methoxybenzoate

Synonym(s):Methyl o-anisate

CAS NO.：606-45-1
Empirical Formula: C9H10O3
Molecular Weight: 166.17
MDL number: MFCD00008423
EINECS: 210-118-6
SAFETY DATA SHEET (SDS)
Update Date: 2023-11-28 16:31:44

What is Methyl 2-methoxybenzoate?

Description

METHYL ο-METHOXYBENZOATE has a herbaceous, anise-like odor with a sweet taste reminiscent of melon. May be prepared by esterification of anisic acid with methanol; or from sodium anisate and dimethylsulfate in the presence of methanol.

Chemical properties

clear colorless to slightly yellow liquid

Chemical properties

Methyl o-methoxybenzoate has an herbaceous, warm, anise-like odor and a sweet taste reminiscent of melon

Occurrence

Reported found in a grape and mushroom variety, Trametes graveolens, Vitis labrusca L. and black tea.

The Uses of Methyl 2-methoxybenzoate

Methyl 2-methoxybenzoate has been used in the synthesis of (+/?)-vibralactone.

Preparation

By esterification of anisic acid with methanol, or from sodium anisate and dimethylsulfate in the presence of methanol

Definition

ChEBI: Methyl 2-methoxybenzoate is a methoxybenzoic acid.

Aroma threshold values

Aroma characteristics at 1.0%: fruity, winey, fermented with a slightly musty and anisic nuance.

Taste threshold values

Taste characteristics at 10 ppm: fruity, anisic, fermented and winey with a good mouthfeel

General Description

FeCl₂ catalyzed cross-coupling reaction between methyl 2-methoxybenzoate and diphenylmethane under various reaction conditions has been investigated.

Properties of Methyl 2-methoxybenzoate

Boiling point:	248 °C (lit.)
Density	1.157 g/mL at 25 °C (lit.)
refractive index	n20/D 1.534(lit.)
FEMA	2717 \| METHYL O-METHOXYBENZOATE
Flash point:	>230 °F
storage temp.	Sealed in dry,Room Temperature
form	clear liquid
color	Colorless to Almost colorless
Specific Gravity	1.16
Odor	at 100.00 %. herbal floral hyacinth cananga fruity blackcurrant
JECFA Number	880
BRN	2207356
Dielectric constant	7.8（21℃）
CAS DataBase Reference	606-45-1(CAS DataBase Reference)
NIST Chemistry Reference	Benzoic acid, 2-methoxy-, methyl ester(606-45-1)
EPA Substance Registry System	Benzoic acid, 2-methoxy-, methyl ester (606-45-1)

Safety information for Methyl 2-methoxybenzoate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection.