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HomeProduct name listMethyl 2-acetamidoacrylate

Methyl 2-acetamidoacrylate

Methyl 2-acetamidoacrylate Structural

What is Methyl 2-acetamidoacrylate?

The Uses of Methyl 2-acetamidoacrylate

Methyl 2-acetamidoacrylate exhibits anti-inflammatory property and decreases induced acute kidney injury in mice.

What are the applications of Application

Methyl 2-acetamidoacrylate is an ethyl pyruvate analog that exhibits anti-inflammatory properties

General Description

Conjugated addition of secondary amines, imidazole and pyrazole to methyl 2 methyl 2-acetamidoacrylate in the presence of a catalyst results in the formation of β-Dialkylamino-α-alanine and β-(N-heteroaryl)-α-alanine derivatives. Methyl-2-acetamidoacrylate (M2AA) is an anti-inflammatory agent. The catalytic reaction of methyl 2-acetamidoacrylate with Grignard′s reagents affords α-amino esters. M2AA can form thermosensitive copolymers with methyl acrylate.

Properties of Methyl 2-acetamidoacrylate

Melting point: 50-52 °C (lit.)
Boiling point: 104 °C/8 mmHg (lit.)
Density  1.3075 (rough estimate)
refractive index  1.4340 (estimate)
Flash point: >230 °F
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Solid
pka 13.12±0.46(Predicted)
color  Off-White
BRN  1812208
CAS DataBase Reference 35356-70-8(CAS DataBase Reference)

Safety information for Methyl 2-acetamidoacrylate

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Methyl 2-acetamidoacrylate

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