Methyl 2-acetamidoacrylate
- CAS NO.：35356-70-8
- Empirical Formula: C6H9NO3
- Molecular Weight: 143.14
- MDL number: MFCD00013394
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-07-12 17:16:24
What is Methyl 2-acetamidoacrylate?
The Uses of Methyl 2-acetamidoacrylate
Methyl 2-acetamidoacrylate exhibits anti-inflammatory property and decreases induced acute kidney injury in mice.
What are the applications of Application
Methyl 2-acetamidoacrylate is an ethyl pyruvate analog that exhibits anti-inflammatory properties
General Description
Conjugated addition of secondary amines, imidazole and pyrazole to methyl 2 methyl 2-acetamidoacrylate in the presence of a catalyst results in the formation of β-Dialkylamino-α-alanine and β-(N-heteroaryl)-α-alanine derivatives. Methyl-2-acetamidoacrylate (M2AA) is an anti-inflammatory agent. The catalytic reaction of methyl 2-acetamidoacrylate with Grignard′s reagents affords α-amino esters. M2AA can form thermosensitive copolymers with methyl acrylate.
Properties of Methyl 2-acetamidoacrylate
| Melting point: | 50-52 °C (lit.) |
| Boiling point: | 104 °C/8 mmHg (lit.) |
| Density | 1.3075 (rough estimate) |
| refractive index | 1.4340 (estimate) |
| Flash point: | >230 °F |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 13.12±0.46(Predicted) |
| color | Off-White |
| BRN | 1812208 |
| CAS DataBase Reference | 35356-70-8(CAS DataBase Reference) |
Safety information for Methyl 2-acetamidoacrylate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Methyl 2-acetamidoacrylate
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