METHANTHELINE BROMIDE
- CAS NO.:53-46-3
- Empirical Formula: CH3-
- Molecular Weight: 15.03452
- MDL number: MFCD00031733
- EINECS: 2001760
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:39
What is METHANTHELINE BROMIDE?
The Uses of METHANTHELINE BROMIDE
METHANTHELINE BROMIDE is a strong muscarinic receptor blocking drug used in the treatment of overactive bladder syndrome, hypersalivation and hyperhidrosis.
The Uses of METHANTHELINE BROMIDE
Ulcine is a strong muscarinic receptor blocking drug used in the treatment of overactive bladder syndrome, hypersalivation and hyperhidrosis.
Definition
ChEBI: Methantheline bromide is a member of xanthenes.
General Description
Methanthelinebromide, diethyl(2-hydroxyethyl)methylammonium bromidexanthene-9-carboxylate (Banthine Bromide), is awhite, slightly hygroscopic, crystalline salt that is solublein water to produce solutions with a pH of about 5.Aqueous solutions are not stable and hydrolyze in a fewdays. The bromide form is preferable to the very hygroscopicchloride.
Among the conditions for which methantheline bromideis indicated are gastritis, intestinal hypermotility, bladderirritability, cholinergic spasm, pancreatitis, hyperhidrosis,and peptic ulcer, all of which are manifestations ofparasympathotonia.
Clinical Use
Methantheline bromide, introduced in 1950, is a potent anticholinergicagent and acts at the nicotinic cholinergic receptors of thesympathetic and parasympathetic systems, as well as at themyoneural junction of the postganglionic cholinergic fibers.Like other quaternary ammonium drugs, methantheline bromideis absorbed incompletely from the GI tract.
Properties of METHANTHELINE BROMIDE
Melting point: | 175-176° |
Density | 1.3380 (rough estimate) |
refractive index | 1.6200 (estimate) |
storage temp. | -20°C Freezer, Under inert atmosphere |
solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
form | Solid |
color | Dark Orange to Very Dark Orange |
Safety information for METHANTHELINE BROMIDE
Computed Descriptors for METHANTHELINE BROMIDE
New Products
Tubulysin F Tubulysin I Tubulysin G Tubulysin M Tubulysin E 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE tetrahydro-4-methyl-2H-pyran 3-Aminocyclobutanone hydrochloride 3-N-BOC-(S)-AMINO BUTYRONITRILE Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate 2H-Pyran, 4-ethynyltetrahydro- 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Calcium Sodium Phosphosilicate IH Fuel shell Imeglimin Hydrochloride IH 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-(2,3-Dihydro- benzofuran-5-yl)-1- morpholin-4-yl- ethanethione 5-(piperazin-1-yl) benzofuran-2- carboxamide Latanoprostene Bunod Magnesium Trisilicate Lubiprostone Flame Retardant Zinc Borate 7-Methoxyquinoline-4-carbonitrileRelated products of tetrahydrofuran
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