Mesaconine
- CAS NO.:6792-09-2
- Empirical Formula: C24H39NO9
- Molecular Weight: 485.57
- MDL number: MFCD29917565
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is Mesaconine?
The Uses of Mesaconine
New use of neoaconitrile in the preparation of medicaments for preventing and/or treating myocardial fibrosis and chronic heart failure caused by myocardial fibrosis
Biological Activity
Mesaconinean, the active ingredient extracted from Aconitum carmichaelii Debx., has cardiovascular effects.
Pharmacology
1) Inhibit or reverse myocardial tissue fibrosis; 2) Improve abnormal cardiac remodeling; 3) Improve cardiac dysfunction; 4) Improve the survival rate of mice with chronic heart failure caused by myocardial fibrosis; 5) Fight against myocardial tissue inflammation; 6 ) Inhibition of cardiomyocyte apoptosis; 7) Myocardial enzyme activity in dead mice, and its mechanism of action is related to inhibiting myocardial tissue inflammation and fibrosis caused by adriamycin and resisting cardiomyocyte apoptosis.
Properties of Mesaconine
Boiling point: | 617.1±55.0 °C(Predicted) |
Density | 1.44±0.1 g/cm3(Predicted) |
solubility | Aqueous Acid (Slightly), Chloroform (Slightly), Methanol (Slightly) |
pka | 12.22±0.70(Predicted) |
form | Solid |
color | White |
Stability: | Moisture Sensitive |
Safety information for Mesaconine
Computed Descriptors for Mesaconine
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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