Mepitiostane
- CAS NO.:21362-69-6
- Empirical Formula: C25H40O2S
- Molecular Weight: 404.65
- MDL number: MFCD00866517
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:44:01
What is Mepitiostane?
Originator
Thioderon,Shionogi,Japan,1979
The Uses of Mepitiostane
An orally active anabolic and androgenic steroid. It is a steroidal anti-estrogen with anti-mammary tumor activity.
Definition
ChEBI: Mepitiostane is an organic molecular entity.
Manufacturing Process
A mixture of 1.759 g of 2α,3α-epithio-5α-androstan-17β-ol, 2.3 ml of 1- methoxycyclopentene, 20 mg of pyridine salt of p-toluenesulfonic acid and 20 ml of t-butanol is stirred for 4 hours at room temperature. The reaction mixture is poured into an aqueous solution of sodium carbonate and the whole extracted with dichloromethane. The extract is dried over anhydrous sodium sulfate and evaporated to remove solvent. Purification of the residue by chromatography over alumina gives 1.487 g of 17β-(1-methoxycyclopentyl) oxy-2α,3α-epithio-5α-androstane. Yield 68.2%. MP 98°C to 101°C.
Therapeutic Function
Antiestrogen
Properties of Mepitiostane
Melting point: | 98-101° |
Boiling point: | 496.21°C (rough estimate) |
alpha | D20 +22.5 ±0.5° (c = 1 in chloroform) |
Density | 0.9998 (rough estimate) |
refractive index | 1.5200 (estimate) |
solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
form | Solid |
color | White to Off-White |
Stability: | Acid Sensitive |
Safety information for Mepitiostane
Computed Descriptors for Mepitiostane
New Products
4-Fluorophenylacetic acid 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate (6-METHYL-[1,3]DITHIOLO[4,5-b]QUINOXALIN-2-ONE INDAZOLE-3-CARBOXYLIC ACID 4-IODO BENZOIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5,6-Dimethoxyindanone 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
You may like
-
2033-24-1 98%View Details
2033-24-1 -
42831-50-5 5-METHYLISOXAZOLE-4-CARBOXYLIC ACID 98%View Details
42831-50-5 -
1975-50-4 98%View Details
1975-50-4 -
2-HYDROXY BENZYL ALCOHOL 98%View Details
90-01-7 -
2-Chloro-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 221615-75-4 98%View Details
221615-75-4 -
61397-56-6 CIS BROMO BENZOATE 98%View Details
61397-56-6 -
14714-50-2 (2-Hydroxyphenyl)acetonitrile 98+View Details
14714-50-2 -
118753-70-1 98+View Details
118753-70-1