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HomeProduct name listMEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE

Synonym(s):N-(Methoxysuccinyl)-L-alanyl-L-alanyl-L-prolyl-L-valine chloromethylketone

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Structural

What is MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE?

The Uses of MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE

A potent irreversible inhibitor of human leukocyte elastase

What are the applications of Application

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone is an inhibitor of neutrophil elastase

Definition

ChEBI: A tripeptide derived from methoxysuccinyl-Ala-Ala-Pro-Val by conversion of the terminal carboxy group to the corresponding chloromethyl ketone.

General Description

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone is a tetrapeptide, cell-permeable and non-cytotoxic inhibitor.

Biochem/physiol Actions

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone acts as a competitive inhibitor of human leukocyte elastase (HLE).

Properties of MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE

Melting point: 159-161 °C
Boiling point: 809.4±65.0 °C(Predicted)
Density  1.234±0.06 g/cm3(Predicted)
storage temp.  -20°C
solubility  ethanol: 50 mg/mL, clear, colorless
pka 13.05±0.20(Predicted)
form  Solid
Sensitive  Moisture Sensitive
BRN  6167019

Safety information for MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE

Computed Descriptors for MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE

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