marcfortine A
- CAS NO.：75731-43-0
- Empirical Formula: C28H35N3O4
- Molecular Weight: 477.602
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-21 10:59:17
What is marcfortine A?
Description
Marcfortine A is an indole alkaloid originally isolated from P. roqueforti. It has nematocidal activity against the parasitic nematode H. contortus (LD99 = 0.06 μg/ml) and inhibits motility of adult worms (EC50 = 2 μM)., Marcfortine A eliminates H. contortus, T. colubriformis, and O. ostertagi from experimentally infected jirds (ED95s = 0.33, 0.11, and 2.5 mg/animal, respectively). It dose-dependently inhibits nicotine-induced calcium mobilization in SH-SY5Y and TE-671 cells expressing α3 subunit-containing human nicotinic acetylcholine receptors (nAChRs) and muscle-type nAChRs, respectively.
The Uses of marcfortine A
Marcfortine A is an indole alkaloid, isolated from Aspergillus and Pencillium species, with potent nematocidal activity. The marcfortines are structurally related to paraherquamides and are thought to act by blocking cholinergic neuromuscular transmission.
The Uses of marcfortine A
Marcfortine A is an indole alkaloid isolated from Aspergillus and Pencillium species.
What are the applications of Application
Marcfortine A is an indole alkaloid isolated from Aspergillus and Pencillium species
Properties of marcfortine A
| Melting point: | 245 °C |
| Boiling point: | 660.6±55.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Methanol: soluble |
| form | A solid |
| pka | 12.05±0.60(Predicted) |
Safety information for marcfortine A
Computed Descriptors for marcfortine A
New Products
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