m-PEG9-COOH
- CAS NO.：2576495-35-5
- Empirical Formula: C20H40O11
- Molecular Weight: 456.52
- MDL number: MFCD27977514
- Update Date: 2024-07-02 08:55:11
What is m-PEG9-COOH?
Biological Activity
m-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Properties of m-PEG9-COOH
| Boiling point: | 536.3±50.0 °C(Predicted) |
| Density | 1.111±0.06 g/cm3(Predicted) |
| pka | 4.28±0.10(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
Safety information for m-PEG9-COOH
Computed Descriptors for m-PEG9-COOH
New Products
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