m-PEG3-Tos
- CAS NO.：50586-80-6
- Empirical Formula: C12H18O5S
- Molecular Weight: 274.33
- MDL number: MFCD13184964
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is m-PEG3-Tos?
Description
m-PEG3-Tos is a PEG linker containing a tosyl group. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
Biological Activity
m-PEG2-Tos is a non-cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs). It can also be used as a PROTAC linker for PROTAC synthesis. .
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Properties of m-PEG3-Tos
| Boiling point: | 392.3±27.0 °C(Predicted) |
| Density | 1.179±0.06 g/cm3(Predicted) |
| form | Solid-Liquid Mixture |
| color | Colorless to white |
Safety information for m-PEG3-Tos
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for m-PEG3-Tos
New Products
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