m-PEG3-Tos
- CAS NO.：50586-80-6
- Empirical Formula: C12H18O5S
- Molecular Weight: 274.33
- MDL number: MFCD13184964
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is m-PEG3-Tos?
Description
m-PEG3-Tos is a PEG linker containing a tosyl group. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
Biological Activity
m-PEG2-Tos is a non-cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs). It can also be used as a PROTAC linker for PROTAC synthesis. .
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Properties of m-PEG3-Tos
| Boiling point: | 392.3±27.0 °C(Predicted) |
| Density | 1.179±0.06 g/cm3(Predicted) |
| form | Solid-Liquid Mixture |
| color | Colorless to white |
Safety information for m-PEG3-Tos
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for m-PEG3-Tos
New Products
ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
![2-[2-(2-METHOXYETHOXY)ETHOXY]ACETIC ACID](https://img.chemicalbook.in/CAS/GIF/16024-58-1.gif)
![2-[2-(2-methoxyethoxy)ethoxy]-ethanethiol](https://img.chemicalbook.in/CAS2/GIF/31521-83-2.gif)
You may like
-
M-Peg3-tos 95% CAS 50586-80-6View Details
50586-80-6 -
Dechloro DesloratadineView Details -
Dehydro DesloratadineView Details -
Edoxaban Impurity 57View Details
2089454-69-1 -
Eltrombopag N-Oxide ImpurityView Details
2734533-17-4 -
Empagliflozin Bromo ImpurityView Details -
Glycopyrronium Bromide EP Impurity IView Details
1404617-94-2 -
Ipratropium EP Impurity BView Details
58073-59-9
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.