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HomeProduct name listLoxoprofen sodium

Loxoprofen sodium

  • CAS NO.:80382-23-6
  • Empirical Formula: C15H19NaO3
  • Molecular Weight: 270.3
  • MDL number: MFCD00941425
  • EINECS: 1806241-263-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-21 22:41:43
Loxoprofen sodium Structural

What is Loxoprofen sodium?

Description

Loxoprofen sodium i s an antiinflammatory/analgesic agent useful in the management of rheumatoid arthritis and related disorders. It is converted in vivo to the corresponding trans-hydroxycyclopentane analog, through which it appears to exert its activity.

Originator

Sankyo (Japan)

The Uses of Loxoprofen sodium

anti-inflammatory

Definition

ChEBI: A hydrate that is the dihydrate form of loxoprofen sodium. The parent acid, loxoprofen, is a prodrug that is rapidly converted to its active trans-alcohol metabolite following oral administration.

brand name

LOXONIN

Mechanism of action

As most NSAIDs, loxoprofen is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid.

Side Effects

Adverse effects include anorexia, nausea, vomiting, bleeding, anemia, diarrhea, and constipation.

Properties of Loxoprofen sodium

storage temp.  Inert atmosphere,Room Temperature
solubility  DMSO: soluble
form  A solid
color  White to off-white
InChI InChI=1S/C15H18O3.Na.H/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16;;/h5-8,10,13H,2-4,9H2,1H3,(H,17,18);;
CAS DataBase Reference 80382-23-6(CAS DataBase Reference)

Safety information for Loxoprofen sodium

Computed Descriptors for Loxoprofen sodium

InChIKey ALZXNWUYLUBHJL-UHFFFAOYSA-N
SMILES C(C1CCCC1=O)C1C=CC(C(C)C(=O)O)=CC=1.[NaH]

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