Lipstatin
- CAS NO.:96829-59-3
- Empirical Formula: C29H49NO5
- Molecular Weight: 491.7
- MDL number: MFCD09838128
- EINECS: 619-246-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is Lipstatin?
The Uses of Lipstatin
Lipstatin, a potent inhibitor of the pancreas lipase, is reported to be useful in the treatment and/or prevention of obesity and related diseases.
The Uses of Lipstatin
Lipstatin is a potent irreversible inhibitor of pancreatic lipase, produced by Streptomyces toxytricini and first reported in 1987. In vivo, lipstatin acts to block the absorption of triglycerides while allowing fatty acid absorption. The tetrahydro analogue of lipstatin, orlistat, although less potent, was developed for the treatment of obesity.
What are the applications of Application
Lipstatin is a potent irreversible inhibitor of pancreatic lipase
Properties of Lipstatin
Boiling point: | 627.4±55.0 °C(Predicted) |
Density | 0.993 |
storage temp. | -20°C Freezer, Under Inert Atmosphere |
solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
form | Oil |
pka | 14.57±0.23(Predicted) |
color | Clear Colorless to Light Yellow |
Safety information for Lipstatin
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Lipstatin
New Products
(R)-3-Aminobutanenitrile Hydrochloride 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION XANTHAN GUM Racecadotril SODIUM VALPROATE Diclofenac Sodium Methylcobalamin (vitamin B12) SODIUM METHYL PARABEN Folic Acid Impurity G Dabigatran Acyl-O2-D-Glucuronide Trifluoroacetic Acid Salt Glycopyrronium Bromide EP Impurity I Eltrombopag N-Oxide Impurity Di-Nitroso Acyclovir Impurity K DLRD N-OxideRelated products of tetrahydrofuran
Orlistat
Orlistat L-Methionine
AHLBNYSZXLDEJQ-FICKONGGSA-N
Orlistat Impurity 32
(2S,3S,5S)-5-[(N-Formyl-L-leucyl)oxy]-2-hexyl-3-hydroxyhexadecanoic Acid (Orlistat Impurity)
(S,S,R,S)-Orlistat
N-ForMyl-L-leucine [S-(E)]-1-(2-Nonenyl)dodecyl Ester
Orlistat Tetradecyl Ester
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