Licochalcone B
- CAS NO.：58749-23-8
- Empirical Formula: C16H14O5
- Molecular Weight: 286.28
- MDL number: MFCD20527294
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-05 19:05:58
What is Licochalcone B?
Chemical properties
Licochalcone B is a yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents,and it is derived from licorice rhizomes.
The Uses of Licochalcone B
Licochalcone B has anti-tumor, anti-inflammatory, and antioxidant effects.It can be used for content determination, identification, pharmacological experiments, etc.
Definition
ChEBI: Licochalcone B is a member of chalcones.
Biological Activity
Licochalcone B is extracted from Glycyrrhizainflate root. LICOCHALCONEB inhibits the self-aggregation of amyloid β (Aβ420) (IC50=2.16 μM) and disintegrates pre-formed Aβ42 fibrils, reducing metal-induced Aβ42 aggregation by chelating metal ions.
Properties of Licochalcone B
| Melting point: | 196-197℃ |
| Boiling point: | 550.5±50.0 °C(Predicted) |
| Density | 1.369±0.06 g/cm3 (20 ºC 760 Torr) |
| storage temp. | Store at -20°C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | powder |
| pka | 7.80±0.15(Predicted) |
| color | White |
Safety information for Licochalcone B
Computed Descriptors for Licochalcone B
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