LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)
Synonym(s):2,5-Dihydroxy-L -tyrosine;3-(2,4,5-Trihydroxyphenyl)-L -alanine
- CAS NO.：27244-64-0
- Empirical Formula: C9H11NO5
- Molecular Weight: 213.19
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:06
What is LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)?
The Uses of LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)
6-Hydroxy-L-DOPA is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase.
The Uses of LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)
6-Hydroxy-L-DOPA (Levodopa EP Impurity A; Levodopa USP Related Compound A) is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase.
Definition
ChEBI: An L-alpha-amino acid that is L-dopa carrying an additional hydroxy substituent at position 6.
Properties of LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)
| Melting point: | >190°C (dec.) |
| Boiling point: | 515.2±38.0 °C(Predicted) |
| Density | 1.606±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Aqueous Acid (Slightly, Sonicated), Water (Slightly, Heated, Sonicated) |
| pka | 2.34±0.25(Predicted) |
| form | neat |
| form | Solid |
| color | Brown to Black |
| Stability: | Air Sensitive, Hygroscopic |
Safety information for LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P501:Dispose of contents/container to..… |
Computed Descriptors for LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)
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KARPSCHEM LABORATORIES PVT. LTD.
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