LATHOSTEROL
Synonym(s):3β-Hydroxy-5α,7-cholestene;5α-cholest-7-en-3β-ol;Lathosterol
- CAS NO.：80-99-9
- Empirical Formula: C27H46O
- Molecular Weight: 386.65
- MDL number: MFCD00056176
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:11
What is LATHOSTEROL?
The Uses of LATHOSTEROL
A Cholesterol (C432501) metabolite. Lathosterol (indicating cholesterol synthesis) and Sitosterol (indicating cholesterol absorption) also decreased with deteriorating health. Low Lathosterol, Sitosterol (S497050), and Cholesterol (C432501) predicted mortality additively and independently of each other.
The Uses of LATHOSTEROL
Lathosterol has been used as a standard for the estimation of the concentrations of cholesterol and plant sterols.
The Uses of LATHOSTEROL
5α-Cholest-7-en-3β-ol was used as a substrate in enzymatic assay for plasma cholesterol. It was used to supplement diet of Daphnia galeata to study the effect on life-history traits.
What are the applications of Application
5α-Cholest-7-en-3β-ol is used as a substrate in enzymatic assay for plasma cholesterol
Definition
ChEBI: A cholestanoid that is (5alpha)-cholest-7-ene substituted by a beta-hydroxy group at position 3.
General Description
Lathosterol is a cholesterol synthesis precursor.
Biochem/physiol Actions
5α-Cholest-7-en-3β-ol (Lathosterol) is an intermediate in cholesterol biosynthesis pathway. Lathosterol in serum is carried on lipoproteins and is indicative of the rate of cholesterol synthesis. It acts as a marker of synthesis of cholesterol and is not affected by dietary consumption of cholesterol.
Properties of LATHOSTEROL
| Melting point: | 126°C |
| Boiling point: | 452.8°C (rough estimate) |
| Density | 0.9610 (rough estimate) |
| refractive index | 1.5250 (estimate) |
| storage temp. | -20°C |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated) |
| form | Solid |
| pka | 15.10±0.70(Predicted) |
| color | White to Off-White |
Safety information for LATHOSTEROL
Computed Descriptors for LATHOSTEROL
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