L-Norleucine
Synonym(s):(S)-(+)-2-Aminohexanoic acid;(S)-2-Aminocaproic acid
- CAS NO.：327-57-1
- Empirical Formula: C6H13NO2
- Molecular Weight: 131.17
- MDL number: MFCD00064423
- EINECS: 206-321-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-19 17:28:17
What is L-Norleucine?
Chemical properties
white to off-white crystalline powder
The Uses of L-Norleucine
As a non-essential amino acid, L-Norleucine can be used as internal standard in amino acid analysis.
The Uses of L-Norleucine
A non-essential amino acid. Used as internal standard in amino acid analysis.
What are the applications of Application
L-(+)-Norleucine is a standard used for amino acid analysis
Definition
ChEBI: A non-proteinogenic L-alpha-amino acid comprising hexanoic acid carrying an amino group at C-2. It does not occur naturally.
Biochem/physiol Actions
L-Norleucine is a synthetic amino acid commonly used as an internal standard.
Purification Methods
Crystallise norleucine from water or aqueous MeOH. [Huffman & Ingersoll J Am Chem Soc 73 3366 1951, Beilstein 4 III 1386, 4 IV 2628.]
Properties of L-Norleucine
| Melting point: | >300 °C (lit.) |
| alpha | 22 º (c=2, 6N HCl) |
| Density | 1.1720 (estimate) |
| refractive index | 23 ° (C=5, 5mol/L HCl) |
| Flash point: | 275 °C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 1.6 g/100 mL (23°C) |
| Boiling point: | 234.0±23.0 °C(Predicted) |
| form | Crystalline Powder |
| pka | 2.335(at 25℃) |
| color | White to off-white |
| Water Solubility | 1.6 g/100 mL (23 ºC) |
| Merck | 14,6706 |
| Sublimation | 275 ºC |
| BRN | 1721750 |
| CAS DataBase Reference | 327-57-1(CAS DataBase Reference) |
| NIST Chemistry Reference | L-Norleucine(327-57-1) |
| EPA Substance Registry System | L-Norleucine (327-57-1) |
Safety information for L-Norleucine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P272:Contaminated work clothing should not be allowed out of the workplace. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. |
Computed Descriptors for L-Norleucine
L-Norleucine manufacturer
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