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HomeProduct name listL-Norleucine

L-Norleucine

Synonym(s):(S)-(+)-2-Aminohexanoic acid;(S)-2-Aminocaproic acid

  • CAS NO.:327-57-1
  • Empirical Formula: C6H13NO2
  • Molecular Weight: 131.17
  • MDL number: MFCD00064423
  • EINECS: 206-321-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-28 13:53:25
L-Norleucine Structural

What is L-Norleucine?

Chemical properties

white to off-white crystalline powder

The Uses of L-Norleucine

As a non-essential amino acid, L-Norleucine can be used as internal standard in amino acid analysis.

The Uses of L-Norleucine

A non-essential amino acid. Used as internal standard in amino acid analysis.

What are the applications of Application

L-(+)-Norleucine is a standard used for amino acid analysis

Definition

ChEBI: A non-proteinogenic L-alpha-amino acid comprising hexanoic acid carrying an amino group at C-2. It does not occur naturally.

Biochem/physiol Actions

L-Norleucine is a synthetic amino acid commonly used as an internal standard.

Purification Methods

Crystallise norleucine from water or aqueous MeOH. [Huffman & Ingersoll J Am Chem Soc 73 3366 1951, Beilstein 4 III 1386, 4 IV 2628.]

Properties of L-Norleucine

Melting point: >300 °C (lit.)
alpha  22 º (c=2, 6N HCl)
Density  1.1720 (estimate)
refractive index  23 ° (C=5, 5mol/L HCl)
Flash point: 275 °C
storage temp.  Sealed in dry,Room Temperature
solubility  1.6 g/100 mL (23°C)
Boiling point: 234.0±23.0 °C(Predicted)
form  Crystalline Powder
pka 2.335(at 25℃)
color  White to off-white
Water Solubility  1.6 g/100 mL (23 ºC)
Merck  14,6706
Sublimation  275 ºC
BRN  1721750
CAS DataBase Reference 327-57-1(CAS DataBase Reference)
NIST Chemistry Reference L-Norleucine(327-57-1)
EPA Substance Registry System L-Norleucine (327-57-1)

Safety information for L-Norleucine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H317:Sensitisation, Skin
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P272:Contaminated work clothing should not be allowed out of the workplace.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

Computed Descriptors for L-Norleucine

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