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HomeProduct name listL-(+)-Glutamic acid hydrochloride

L-(+)-Glutamic acid hydrochloride

Synonym(s):(S)-2-Aminoglutaric acid;(S)-2-Aminopentanedioic acid ammonium salt;2-Aminoglutaric acid hydrochloride;Glu HCl;L-Glutamic acid hydrochloride

  • CAS NO.:138-15-8
  • Empirical Formula: C5H10ClNO4
  • Molecular Weight: 183.59
  • MDL number: MFCD00012619
  • EINECS: 205-315-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-14 18:30:21
L-(+)-Glutamic acid hydrochloride Structural

What is L-(+)-Glutamic acid hydrochloride?

Chemical properties

white crystals or fine crystalline powder

The Uses of L-(+)-Glutamic acid hydrochloride

Glutamic Acid Hydrochloride is a flavoring, salt substitute that is soluble in water and very slightly soluble in alcohol and ether. It is obtained by chemical synthesis.

The Uses of L-(+)-Glutamic acid hydrochloride

L-Glutamic acid hydrochloride is used as a digestive aid. It is used in cell culture as a component of MEM non-essential amino acids solution. It has been used as a nitrogen source in the culture of Aspergillus fumigatus NRRL 2436 for fumagillin production.

General Description

L-glutamate is the major excitatory neurotransmitter in mammalian central nervous system (CNS). It interacts with membrane bound glutamate receptors.

Biochem/physiol Actions

L-glutamate plays key roles in development, learning, memory, plasticity and cognition. It plays crucial role in the pathogenesis of neuropathological diseases such as epilepsy, schizophrenia, stroke, ischemia, ALS (amyotrophic lateral sclerosis), Huntington′s disease and Parkinson′s disease. Glutamate is also responsible for the activation of long-term potentiation (LTP) and long-term depression (LTD). Induction of glutamate receptors plays a key role in the pathophysiology of migraine.

Properties of L-(+)-Glutamic acid hydrochloride

Melting point: 214 °C (dec.)(lit.)
alpha  25.5 º (c=10, 2N HCl)
Density  1.525
refractive index  24 ° (C=6, H2O)
storage temp.  Store below +30°C.
solubility  H2O: 1 M at 20 °C, clear, colorless
form  Crystals For Fine Crystalline Powder
color  White
Odor at 100.00?%. odorless
Water Solubility  490 g/L (20 ºC)
Sensitive  Hygroscopic
Merck  14,4469
BRN  3565569
Stability: Hygroscopic
CAS DataBase Reference 138-15-8(CAS DataBase Reference)
EPA Substance Registry System L-Glutamic acid, hydrochloride (138-15-8)

Safety information for L-(+)-Glutamic acid hydrochloride

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H314:Skin corrosion/irritation
Precautionary Statement Codes P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P363:Wash contaminated clothing before reuse.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for L-(+)-Glutamic acid hydrochloride

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