L-ETHIONINE
Synonym(s):L -2-Amino-4-(ethylthio)butyric acid
- CAS NO.：13073-35-3
- Empirical Formula: C6H13NO2S
- Molecular Weight: 163.24
- MDL number: MFCD00002626
- EINECS: 235-966-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is L-ETHIONINE?
Chemical properties
White Solid
The Uses of L-ETHIONINE
Ethionine-induced inhibition of protein synthesis and lowering of ATP level in the liver.
Definition
ChEBI: An S-ethylhomocysteine that has S-configuration at the chiral centre.
Purification Methods
Likely impurities are N-acetyl-(R and S)-ethionine, S-methionine, and R-ethionine. Crystallise it from water by adding 4volumes of EtOH or 85% aqueous EtOH. It sublimes at 196-216o/0.3mm with 99.1% recovery and unracemised [Gross & Gradsky J Am Chem Soc 77 1678 1955]. [Weiss & Stekol J Am Chem Soc 73 2399 1951, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2658, 2659 1961, Beilstein 4 IV 3194.]
Properties of L-ETHIONINE
| Melting point: | 280 °C (dec.)(lit.) |
| alpha | D24 +25.1°; D23 +20.1° (1N HCl) (Armstrong, Lewis) |
| Density | 1.085 (estimate) |
| refractive index | 22 ° (C=1, 1mol/L HCl) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | Aqueous Acid (Slightly), Water (Slightly) |
| form | solid |
| Boiling point: | 310.4±37.0 °C(Predicted) |
| pka | 2.23±0.10(Predicted) |
| color | White to Off-White |
| Merck | 14,3738 |
| CAS DataBase Reference | 13073-35-3(CAS DataBase Reference) |
| EPA Substance Registry System | L-Ethionine (13073-35-3) |
Safety information for L-ETHIONINE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for L-ETHIONINE
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Mefenamic Acid IP/BP/EP/USP Diclofenac Sodium IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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