L-DITHIOTHREITOL
Synonym(s):(−)-Cleland’s Reagent;(2R,3R)-1,4-Dimercapto-2,3-butanediol;L -DTT;Cleland reagent chiral
- CAS NO.:16096-97-2
- Empirical Formula: C4H10O2S2
- Molecular Weight: 154.25
- MDL number: MFCD00064305
- EINECS: 240-263-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-30 18:52:02
What is L-DITHIOTHREITOL?
Chemical properties
white crystalline powder
The Uses of L-DITHIOTHREITOL
L-DTT [(2R,3R)-1,4-dimercapto-2,3-butanediol; L-dithiothreitol], a chiral bidentate dithiol with two stereogenic centers, may be used in chiroptical response research. L-DDT is proposed as a stereoselective reducing agent for disulfide bridges in complex molecules.
What are the applications of Application
L-1,4-Dithiothreitol is a stereoselective reducing agent for disulfide bridges in complex molecules
Definition
ChEBI: L-1,4-dithiothreitol is a 1,4-dithiothreitol. It is an enantiomer of a D-1,4-dithiothreitol.
Properties of L-DITHIOTHREITOL
Melting point: | 51 °C |
Boiling point: | 247.65°C (rough estimate) |
Density | 1.156 (estimate) |
refractive index | 26 ° (C=2.5, MeOH) |
Flash point: | 110 °C |
storage temp. | -20°C |
solubility | H2O: soluble50mg/mL, clear to hazy, colorless |
form | solid |
pka | 9.28±0.10(Predicted) |
color | White to Almost white |
BRN | 2036371 |
CAS DataBase Reference | 16096-97-2(CAS DataBase Reference) |
Safety information for L-DITHIOTHREITOL
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H412:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P273:Avoid release to the environment. |
Computed Descriptors for L-DITHIOTHREITOL
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L-DITHIOTHREITOL
1,4-BUTANEDITHIOL
DITHIOTHREITOL AND ALPHA-THIOGLYCEROL
DL-1,4-DITHIOTHREITOL (D10),1,4-DITHIOTHREITOL-D10,1,4-DITHIOTHREITOL-D10, 98 ATOM % D
{DL-DITHIOTHREITOL--N/H
DITHIOTHREITOL SOLUTION 1000UG/ML IN ETHYL ACETATE 1ML
DTT / TG11 [DITHIOTHREITOL + ALPHA-THIOGLYCEROL (1:1 MIXTURE)][MATRIX FOR FABMS AND LIQUID SIMS]
{ DITHIOTHREITOL (DTT) - 5G
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