Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listL-CYCLOSERINE

L-CYCLOSERINE

Synonym(s):(S)-4-Amino-3-isoxazolidone

  • CAS NO.:339-72-0
  • Empirical Formula: C3H6N2O2
  • Molecular Weight: 102.09
  • MDL number: MFCD00064324
  • EINECS: 206-427-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-30 20:13:01
L-CYCLOSERINE Structural

What is L-CYCLOSERINE?

Chemical properties

WHITE GRANULAR POWDER

The Uses of L-CYCLOSERINE

L-Cycloserine is an irreversible inhibitor of 3-ketodihydrosphingosine synthetase.

The Uses of L-CYCLOSERINE

antibacterial, coccidiostat

What are the applications of Application

L-Cycloserine is an irreversible inhibitor of 3-ketodihydrosphingosine synthetase

Definition

ChEBI: A 4-amino-1,2-oxazolidin-3-one that has S configuration. An antibiotic isolated from Erwinia uredovora.

Biochem/physiol Actions

L-cycloserine is a potent inhibitor of serine palmitoyltransferase, the first step of sphingolipid synthesis.

Purification Methods

Purify cycloserine by recrystallisation from aqueous EtOH or MeOH or aqueous NH3/EtOH or isoPrOH. Also recrystallise it from aqueous ammoniacal solution at pH 10.5 (100mg/mL) by diluting with 5 volumes of isopropanol and then adjusting to pH 6 with acetic acid. An aqueous solution, buffered to pH 10 with Na2CO3, can be stored in a refrigerator for 1week without decomposition. UV: max at 226nm (A1cm 1% 4.02). The tartrate salt has m 165-166o (dec), 166-168o (dec), and [] D 24 -41o (c 0.7, H2O). [Stammer et al. J Am Chem Soc 79 3236 1959, UV: Kuehl J Am Chem Soc 77 2344 1955, Beilstein 27 III/IV 5549.]

Properties of L-CYCLOSERINE

Melting point: 147 °C
Boiling point: 191.38°C (rough estimate)
Density  1.278
refractive index  1.5110 (estimate)
storage temp.  Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility  H2O: soluble50mg/mg protein
form  White to off-white powder.
pka 14.36±0.40(Predicted)
color  White to Off-White
BRN  80799
CAS DataBase Reference 339-72-0(CAS DataBase Reference)

Safety information for L-CYCLOSERINE

Signal word Warning
Pictogram(s)
ghs
Flame
Flammables
GHS02
GHS Hazard Statements H226:Flammable liquids
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233:Keep container tightly closed.
P240:Ground/bond container and receiving equipment.
P241:Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242:Use only non-sparking tools.
P243:Take precautionary measures against static discharge.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P370+P378:In case of fire: Use … for extinction.
P403+P235:Store in a well-ventilated place. Keep cool.

Computed Descriptors for L-CYCLOSERINE

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.