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HomeProduct name listL-Arginine alpha-ketoglutarate

L-Arginine alpha-ketoglutarate

  • CAS NO.:16856-18-1
  • Empirical Formula: C11H20N4O7
  • Molecular Weight: 320.3
  • MDL number: MFCD00216455
  • EINECS: 240-882-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-05-06 16:28:20
L-Arginine alpha-ketoglutarate Structural

What is L-Arginine alpha-ketoglutarate?

Description

L-arginine α-ketoglutarate (L-Arginine alpha-ketoglutarate) is a unique amino acid derivative, constituted by a combination of two L-arginine molecules and one 2-oxoglutarate molecule. This compound has attracted considerable interest in the past few years because of its potential use in various scientific research applications and its noteworthy biochemical and physiological effects. L-arginine α-ketoglutarate has showcased versatility in research, serving as an enzyme reaction substrate, a stabilizing agent for proteins and enzymes, and an antioxidant. It has also been employed in studies that examine the impact of various substances and potential toxins on the human body. While the exact mechanism of action of L-Arginine α-ketoglutarate is yet to be fully deciphered, it is speculated that it plays a role in the manufacture of nitric oxide, a significant signaling molecule involved in numerous physiological processes. Furthermore, L-Arginine α-ketoglutarate is believed to participate in the regulation of both cellular metabolism and gene expression.

The Uses of L-Arginine alpha-ketoglutarate

L-arginine alpha-ketoglutarate is a natural product. It has been shown to enhance the release of NO in the body. It is suggested that muscular performance be facilitated by increasing blood flow and oxygen and nutrient delivery to the working muscle[1-2].

The Uses of L-Arginine alpha-ketoglutarate

[1] Wax, B. et al. “Effect of L-Arginine Alpha-Ketoglutarate Ingestion on Muscular Strength and Endurance.” 2011. 0.
[2] Benjamin Wax. “Acute L-arginine alpha ketoglutarate supplementation fails to improve muscular performance in resistance trained and untrained men.” Journal of the International Society of Sports Nutrition 9 1 (2012): 17.

Properties of L-Arginine alpha-ketoglutarate

storage temp.  2-8°C
InChI InChI=1/C6H14N4O2.C5H6O5/c7-4(5(11)12)2-1-3-10-6(8)9;6-3(5(9)10)1-2-4(7)8/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1-2H2,(H,7,8)(H,9,10)/t4-;/s3
CAS DataBase Reference 16856-18-1(CAS DataBase Reference)

Safety information for L-Arginine alpha-ketoglutarate

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for L-Arginine alpha-ketoglutarate

InChIKey PGRNZHOQVAPMFX-NDILARRWNA-N
SMILES C([C@H](N)C(=O)O)CCNC(N)=N.C(=O)(C(=O)O)CCC(=O)O |&1:1,r|

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