L-701,324
Synonym(s):7-Chloro-4-hydroxy-3-(3-phenoxy)phenylquinolin-2[1H]-one
- CAS NO.：142326-59-8
- Empirical Formula: C21H14ClNO3
- Molecular Weight: 363.79
- MDL number: MFCD00910917
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-13 18:13:23
What is L-701,324?
The Uses of L-701,324
L-701,324 is a potential anticonvulsant with high selectivity and affinity for the NMDA receptor glycine site. NMDA receptors are expressed by small-cell lung cancer and are potential targets for effective treatment.
What are the applications of Application
L-701,324 is a potential anticonvulsant with high selectivity and affinity for the NMDA receptor glycine site.
Definition
ChEBI: 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-1H-quinolin-2-one is a member of quinolines.
Biological Activity
An orally active and long acting anticonvulsant with high affinity and selectivity for the glycine site on the NMDA receptor.
storage
Store at RT
Properties of L-701,324
| Melting point: | 308 °C |
| Boiling point: | 584.7±50.0 °C(Predicted) |
| Density | 1.389±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO: soluble36.4mg/mL |
| form | solid |
| pka | 4.50±1.00(Predicted) |
| color | White to off-white |
Safety information for L-701,324
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for L-701,324
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