L-5,5-Dimethylthiazolidine-4-carboxylic acid

Synonym(s):DTC

CAS NO.：72778-00-8
Empirical Formula: C6H11NO2S
Molecular Weight: 161.22
MDL number: MFCD00070264
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-26 08:28:20

L-5,5-Dimethylthiazolidine-4-carboxylic acid Structural

What is L-5,5-Dimethylthiazolidine-4-carboxylic acid?

Chemical properties

White Solid

The Uses of L-5,5-Dimethylthiazolidine-4-carboxylic acid

Found to act on the cell membrane of tumour cells, possible causing a reverse transformation to normal cells through restoration of contact inhibition.

What are the applications of Application

L-5,5-Dimethylthiazolidine-4-carboxylic acid is a possible antitumor agent

Biological Activity

L-5,5-Dimethylthiazolidine-4-carboxylic acid (DTC) is used as a proline analog with restricted conformation in studies on receptor bound conformational requirements for agonists and antagonists of angiotensin II (ANG II).

Properties of L-5,5-Dimethylthiazolidine-4-carboxylic acid

Melting point:	206°C dec.
Boiling point:	317.3±37.0 °C(Predicted)
Density	1.195±0.06 g/cm3(Predicted)
refractive index	[a]20D = - 149 ± 2 o (C=1 in water)
storage temp.	2-8°C
solubility	Dichloromethane, DMSO, Methanol
form	Solid
pka	2.11±0.40(Predicted)
color	White to off-white powder

Safety information for L-5,5-Dimethylthiazolidine-4-carboxylic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.