L-4,4'-BIPHENYLALANINE
- CAS NO.：155760-02-4
- Empirical Formula: C15H15NO2
- Molecular Weight: 241.29
- MDL number: MFCD01318878
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 20:33:22
What is L-4,4'-BIPHENYLALANINE?
Description
4-Biphenylyl-L-alanine (BipA) is a synthetic amino acid that was prepared to put a?“leash” on genetically modified?Escherichia coli.?It replaces phenylalanine in the codon of unmodified?E. coli. Additional phenylalanine derivatives have been made for the same purpose.
G. M. Church at Harvard Medical School and F. J. Isaacs at Yale University are using?E. coli?as a model to explore ways to prevent genetically modified organisms (GMOs) from reproducing in the environment. Tagging a GMO with a non-natural amino acid such as BipA allows it to reproduce in the laboratory but not in nature. If this strategy is successful, the next step would be to extend it to commercial GMOs such as crop plants.
The Uses of L-4,4'-BIPHENYLALANINE
L-4,4''-Biphenylalanine is a useful reagent in the preparation of other biologically active small molecules.
Properties of L-4,4'-BIPHENYLALANINE
| Melting point: | 227° - 229°C |
| Boiling point: | 428.6±40.0 °C(Predicted) |
| Density | 1.190±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Acidic DMSO (Slightly) |
| form | Solid |
| pka | 2.21±0.10(Predicted) |
| color | White to Off-White |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 155760-02-4(CAS DataBase Reference) |
Safety information for L-4,4'-BIPHENYLALANINE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for L-4,4'-BIPHENYLALANINE
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid DIETHYL AMINOMALONATE HYDROCHLORIDE 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
![METHYL (2S)-2-AMINO-3-[4-(4-FLUOROPHENYL)PHENYL]PROPANOATE](https://img.chemicalbook.in/StructureFile/ChemBookStructure9/GIF/CB3159048.gif)
![METHYL (2S)-2-AMINO-3-[4-(3,4-DICHLOROPHENYL)PHENYL]PROPANOATE](https://img.chemicalbook.in/StructureFile/ChemBookStructure9/GIF/CB6712183.gif)
![METHYL (2S)-2-AMINO-3-(4-[4-(TRIFLUOROMETHYL)PHENYL]PHENYL)PROPANOATE](https://img.chemicalbook.in/StructureFile/ChemBookStructure9/GIF/CB1227444.gif)
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