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kijanimicin

kijanimicin Structural

What is kijanimicin?

The Uses of kijanimicin

Kijanimicin is a tetronic acid related to saccharocarcin, chlorothricin, versipelostatin and tetrocarcin. Like the tetrocarcins, kijanimicin contains an unusual nitroaminoglycoside. Kijanimicin is a potent antibacterial, antimalarial and antitumour active. Several members of this class have received considerable literature focus. Versipelostatin inhibits transcription from the promoter of GRP78, a gene that is activated as part of a stress signalling pathway under glucose deprivation resulting in unfolded protein response (UPR). The UPR-inhibitory action is seen only in conditions of glucose deprivation and causes selective and massive killing of the glucose-deprived cells. Tetrocarcin A appears to target the phosphatidylinositide-3'-kinase/Akt signalling pathway.

The Uses of kijanimicin

Kijanimicin is an antibacterial tetronic acid compound.

What are the applications of Application

Kijanimicin is an antibacterial tetronic acid compound

Properties of kijanimicin

Density  1.35±0.1 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form  A solid
pka 4.50±1.00(Predicted)

Safety information for kijanimicin

Computed Descriptors for kijanimicin

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