JACOLINE
- CAS NO.：480-76-2
- Empirical Formula: C18H27NO7
- Molecular Weight: 369.41
- MDL number: MFCD00871325
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-07-12 17:04:18
What is JACOLINE?
Description
A pyrrolizidine alkaloid which is found in Senecio Jacobea, this base has [α]20D + 48° (CHC13 ) and is hydrolyzed by alkalies to retronecine and jacolinecic acid, ClOH1S0 7. The latter contains three hydroxyl and three methyl groups.
The Uses of JACOLINE
Jacoline is a potentially carcinogenic, mutagenic, and teratogenic hepatotoxic alkaloid found in the nectar of tansy ragwort (S. jacobaea).
References
Bradbury, Culvenor., Chern. & Ind., 1021 (1954)
Bradbury, Culvenor., Austral. J. Chern., 7,378 (1954)
Bradbury, Willis., ibid, 9,258 (1956)
Geissman" ibid, 12,247 (1959)
Properties of JACOLINE
| Melting point: | 221°C |
| Boiling point: | 583.5±50.0 °C(Predicted) |
| Density | 1.36±0.1 g/cm3(Predicted) |
| pka | 12.40±0.60(Predicted) |
Safety information for JACOLINE
Computed Descriptors for JACOLINE
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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