Isoquinoline, 1,7-dichloro-4-Methoxy-

CAS NO.：630423-36-8
Empirical Formula: C10H7Cl2NO
Molecular Weight: 228.07
MDL number: MFCD17012717
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 17:06:38

What is Isoquinoline, 1,7-dichloro-4-Methoxy-?

The Uses of Isoquinoline, 1,7-dichloro-4-Methoxy-

1,7-Dichloro-4-methoxyisoquinoline acts as a reagent in the synthesis and biological evaluations of P4-benzoxaborole-substituted macrocyclic inhibitors of HCV NS3 protease. Preparation, SAR of methoxyisoquinoline derivatives and discovery of asunaprevir (BMS-650032), an orally efficacious NS3 protease inhibitor for the treatment of hepatitis C virus infection.

Properties of Isoquinoline, 1,7-dichloro-4-Methoxy-

Melting point:	137.0 to 142.0 °C
Boiling point:	355.7±37.0 °C(Predicted)
Density	1.384±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
form	powder to crystal
pka	0.98±0.34(Predicted)
color	White to Yellow to Orange

Safety information for Isoquinoline, 1,7-dichloro-4-Methoxy-

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention.