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HomeProduct name listIsoniazid-D4

Isoniazid-D4

Isoniazid-D4 Structural

What is Isoniazid-D4?

Chemical properties

Crystalline Solid

The Uses of Isoniazid-D4

Labelled Isoniazid. Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antibacterial (tuberculostatic).

What are the applications of Application

Isoniazid-d4 is an inhibitor and an inducer of various isoforms of CYP450

Properties of Isoniazid-D4

Melting point: 171.40C
storage temp.  Refrigerator
solubility  DMSO (Slightly), Methanol (Slightly)
form  Solid
color  White to Pale Beige

Safety information for Isoniazid-D4

Computed Descriptors for Isoniazid-D4

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