ISOMITRAPHYLLINE
Synonym(s):Ajmalicine oxindole A
- CAS NO.:4963-01-3
- Empirical Formula: C21H24N2O4
- Molecular Weight: 368.43
- MDL number: MFCD03788776
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:24
What is ISOMITRAPHYLLINE?
Description
This Mitragyna alkaloid has been isolated from the leaves of M. speciosa Korth by Beckett and his colleagues. It is an amorphous solid which cannot be obtained crystalline. The base may be characterized as the picrate which forms pale yellow needles from MeOH, m.p. 223°C (dec.). A methylgroup, a methoxycarbonyl group and one imino group are present. The second nitrogen atom is tertiary.
The Uses of ISOMITRAPHYLLINE
Isomitraphylline is an oxoindole alkaloid derivied from amazonian plants and maintain medicinal benefits. Used in the treatment of ulcers, arthritis, etc.
References
Beckett et al., J. Pharm. Pharmacol., 17,753 (1965) Beckett et ai., Planta Med., 14, 266 (1966) Structure: Finch, Taylor., J. Amer. Chem. Soc., 84,3871 (1962) Prepara tion: Seaton et al., Can. J. Chem., 38, 1035 (1960)
Properties of ISOMITRAPHYLLINE
Boiling point: | 555.2±50.0 °C(Predicted) |
Density | 1.33±0.1 g/cm3(Predicted) |
storage temp. | -20°C |
pka | 13.56±0.60(Predicted) |
Safety information for ISOMITRAPHYLLINE
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H300:Acute toxicity,oral |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for ISOMITRAPHYLLINE
New Products
2,2-diethoxyethanethioamide (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin H 4-(Benzyloxy)-3-bromophenylacetic Acid 3-METHYLAZETIDIN-3-OL HYDROCHLORIDE 2,2-Difluoropropylamine hydrochloride CYCLOBUTYLAMINE HYDROCHLORIDE 4,4-DIFLUOROCYCLOHEXANAMINE 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Imeglimin Hydrochloride IH (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Fuel shell 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Magnesium Trisilicate Lubiprostone Latanoprostene Bunod Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate 7-Methoxyquinoline-4-carbonitrile 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acidRelated products of tetrahydrofuran
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