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HomeProduct name listISOMITRAPHYLLINE

ISOMITRAPHYLLINE

Synonym(s):Ajmalicine oxindole A

ISOMITRAPHYLLINE Structural

What is ISOMITRAPHYLLINE?

Description

This Mitragyna alkaloid has been isolated from the leaves of M. speciosa Korth by Beckett and his colleagues. It is an amorphous solid which cannot be obtained crystalline. The base may be characterized as the picrate which forms pale yellow needles from MeOH, m.p. 223°C (dec.). A methylgroup, a methoxycarbonyl group and one imino group are present. The second nitrogen atom is tertiary.

The Uses of ISOMITRAPHYLLINE

Isomitraphylline is an oxoindole alkaloid derivied from amazonian plants and maintain medicinal benefits. Used in the treatment of ulcers, arthritis, etc.

References

Beckett et al., J. Pharm. Pharmacol., 17,753 (1965) Beckett et ai., Planta Med., 14, 266 (1966) Structure: Finch, Taylor., J. Amer. Chem. Soc., 84,3871 (1962) Prepara tion: Seaton et al., Can. J. Chem., 38, 1035 (1960)

Properties of ISOMITRAPHYLLINE

Boiling point: 555.2±50.0 °C(Predicted)
Density  1.33±0.1 g/cm3(Predicted)
storage temp.  -20°C
pka 13.56±0.60(Predicted)

Safety information for ISOMITRAPHYLLINE

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H300:Acute toxicity,oral
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P405:Store locked up.
P501:Dispose of contents/container to..…

Computed Descriptors for ISOMITRAPHYLLINE

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