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HomeProduct name listiopydol

iopydol

  • CAS NO.:5579-92-0
  • Empirical Formula: C8H9I2NO3
  • Molecular Weight: 420.97
  • MDL number: MFCD00867925
  • EINECS: 226-968-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-04 17:34:40
iopydol Structural

What is iopydol?

Originator

Hytrast Vial,Guerbet

The Uses of iopydol

Iopydol is the X-ray contrast reagent.

The Uses of iopydol

Diagnostic aid (radiopaque medium, bronchographic) .

Definition

ChEBI: Iopydol is a chloropyridine.

Manufacturing Process

50 g 4-pyridone was dissolved in 300 ml 20% hydrochloric acid and slowly mixed with 180 g of chloroiodide in 200 ml 20% hydrochloric acid. Then the obtained dark solution was strong alkalized with sodium hydroxide. The solvent was removed to dryness and sodium salt diiod-4-pyridone was
obtained. It was dissolved in water, filtered and equivalent quantity of glacial acetic acid or hydrochloric acid was added to give 3,5-diiod-4-pyridone as a powder. 34.5 g 3,5-diiod-pyridone was dissolved in 100 ml 1 N NaOH by heating on a water bath and added to a 15 g of monochlorohydrine added. The mixture was heated on water bath before a dense pasty mass obtained. It was filtered off and treated with 1 N NaOH. The obtained 1-(2,3- dihydroxypropyl)-3,5-diiodo-4(1H)-pyridinone was recrystallized from diluted hydrochloric acid. MP: 161°C.

Therapeutic Function

Diagnostic aid

Properties of iopydol

Melting point: 161°

Safety information for iopydol

Computed Descriptors for iopydol

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