iopydol
- CAS NO.:5579-92-0
- Empirical Formula: C8H9I2NO3
- Molecular Weight: 420.97
- MDL number: MFCD00867925
- EINECS: 226-968-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:40
What is iopydol?
Originator
Hytrast Vial,Guerbet
The Uses of iopydol
Iopydol is the X-ray contrast reagent.
The Uses of iopydol
Diagnostic aid (radiopaque medium, bronchographic) .
Definition
ChEBI: Iopydol is a chloropyridine.
Manufacturing Process
50 g 4-pyridone was dissolved in 300 ml 20% hydrochloric acid and slowly
mixed with 180 g of chloroiodide in 200 ml 20% hydrochloric acid. Then the
obtained dark solution was strong alkalized with sodium hydroxide. The
solvent was removed to dryness and sodium salt diiod-4-pyridone was
obtained. It was dissolved in water, filtered and equivalent quantity of glacial
acetic acid or hydrochloric acid was added to give 3,5-diiod-4-pyridone as a
powder. 34.5 g 3,5-diiod-pyridone was dissolved in 100 ml 1 N NaOH by
heating on a water bath and added to a 15 g of monochlorohydrine added.
The mixture was heated on water bath before a dense pasty mass obtained. It
was filtered off and treated with 1 N NaOH. The obtained 1-(2,3-
dihydroxypropyl)-3,5-diiodo-4(1H)-pyridinone was recrystallized from diluted
hydrochloric acid. MP: 161°C.
Therapeutic Function
Diagnostic aid
Properties of iopydol
Melting point: | 161° |
Safety information for iopydol
Computed Descriptors for iopydol
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