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HomeProduct name listIndole-4-carboxylic acid

Indole-4-carboxylic acid

Synonym(s):4-Carboxyindole

  • CAS NO.:2124-55-2
  • Empirical Formula: C9H7NO2
  • Molecular Weight: 161.16
  • MDL number: MFCD00009739
  • EINECS: 621-279-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
Indole-4-carboxylic acid Structural

What is Indole-4-carboxylic acid?

Chemical properties

Beige powder

The Uses of Indole-4-carboxylic acid

  • Reactant for preparation of substituted indole derivatives as histamine H3 antagonists
  • Reactant for preparation of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1
  • Reactant for preparation of inhibitors of Gli1-mediated transcription in Hedgehog pathway
  • Reactant for preparation of pyridinyl carboxylates as SARS-CoV 3CL proinhibitors
  • Reactant for preparation of substituted bipiperidinylmethyl amides as CCR3 membrane binding ligands
  • Reactant for preparation of indole amide hydroxamic acids as potent inhibitors of histone deacetylases
  • Reactant for preparation of 2-[[[4′-chloro-[1,1-biphenyl]-4-yl]thio]methyl]-N-hydroxybutanamide derivatives as specific metalloproteinase

Properties of Indole-4-carboxylic acid

Melting point: 213-214 °C (lit.)
Boiling point: 213-214℃
Density  1.408±0.06 g/cm3(Predicted)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
pka 3.90±0.10(Predicted)
form  Powder
color  Beige
InChI InChI=1S/C9H7NO2/c11-9(12)7-2-1-3-8-6(7)4-5-10-8/h1-5,10H,(H,11,12)
CAS DataBase Reference 2124-55-2(CAS DataBase Reference)

Safety information for Indole-4-carboxylic acid

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Indole-4-carboxylic acid

InChIKey ROGHUJUFCRFUSO-UHFFFAOYSA-N
SMILES N1C2=C(C(C(O)=O)=CC=C2)C=C1

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