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HomeProduct name listICI 204,448 HYDROCHLORIDE

ICI 204,448 HYDROCHLORIDE

Synonym(s):(±)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride;R,S-[3-[1-[[(3,4-Dichlorophenyl)acetyl]methylamino]-2-(1-pyrrolidinyl)ethyl] phenoxy]-acetic acid hydrochloride

ICI 204,448 HYDROCHLORIDE Structural

What is ICI 204,448 HYDROCHLORIDE?

The Uses of ICI 204,448 HYDROCHLORIDE

Opioid agonists exert a broad range of effects on the immune system ranging from inflammatory response modulation to opioid and chemokine receptor expression. ICI 204448 is a kappa-opioid receptor with antinociceptive properties.

What are the applications of Application

ICI-204,448 hydrochloride is a peripherally acting KOR (κ-opioid receptor) agonist.

Biological Activity

Peripherally acting κ agonist.

storage

Store at RT

Properties of ICI 204,448 HYDROCHLORIDE

storage temp.  Store at RT
solubility  45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 12 mg/mL
form  solid
color  white

Safety information for ICI 204,448 HYDROCHLORIDE

Computed Descriptors for ICI 204,448 HYDROCHLORIDE

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