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HomeProduct name listICI-118,551

ICI-118,551

Synonym(s):(±)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride;(2R,3R)-rel-3-isopropylamino-1-(7-methylindan-4-yloxy)-butan-2-ol hydrochloride;ICI 118551 Hydrochloride - CAS 72795-19-8 - Calbiochem

ICI-118,551 Structural

What is ICI-118,551?

The Uses of ICI-118,551

The (R,R)-enantiomer of ICI 118551 as highly selective β2-adrenoceptor antagonist. The S,S-enantiomer is the most potent.

Definition

ChEBI: ICI 118551 is an indane substituted at position 7 by a methyl group and at position 4 by a 3-(isopropylamino)-2-hydroxybutoxy group (the 2R,3S-diastereomer). It has a role as a beta-adrenergic antagonist. It is a member of indanes, an aromatic ether, a secondary alcohol and a secondary amino compound.

Properties of ICI-118,551

Melting point: 217-219°C
Boiling point: 439.3±45.0 °C(Predicted)
Density  1.045±0.06 g/cm3(Predicted)
storage temp.  Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility  ethanol: 7.3 mg/mL
form  powder
pka 13.87±0.20(Predicted)
color  white

Safety information for ICI-118,551

Computed Descriptors for ICI-118,551

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