IB-MECA
Synonym(s):1-Deoxy-1-[6-[((3-Iodophenyl)methyl)amino]-9H-purin-9-yl]-N-methyl-β-D -ribofuranuronamide;N6-(3-Iodobenzyl)adenosine-5′-N-methyluronamide
- CAS NO.:152918-18-8
- Empirical Formula: C18H19IN6O4
- Molecular Weight: 510.29
- MDL number: MFCD00671785
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 15:53:33
What is IB-MECA?
The Uses of IB-MECA
IB-MECA has been used for intraocular pressure and corneal thickness measurements in rabbits.
What are the applications of Application
IB-MECA is a potent and selective Adenosine A3-R agonist
Definition
ChEBI: A derivative of adenosine in which the 5'-hydroxymethyl group is replaced by N-ethylcarboxamido and one of the hydrogens of the exocyclic amino function is substituted by a 3-iodobenzyl group.
Biological Activity
Potent and selective A 3 adenosine receptor agonist (K i values are 1.1, 54 and 56 nM for A 3 , A 1 and A 2A receptors respectively). Cardioprotective, reduces infarct size upon reperfusion in rats.
Biochem/physiol Actions
Selective A3 adenosine receptor agonist.
storage
Desiccate at +4°C
Properties of IB-MECA
Density | 1.98±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | hot ethanol: >10 mg/mL |
pka | 12.72±0.70(Predicted) |
form | solid |
color | white |
Safety information for IB-MECA
Computed Descriptors for IB-MECA
InChIKey | HUJXGQILHAUCCV-MOROJQBDSA-N |
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Mefenamic Acid IP/BP/EP/USP Diclofenac Sodium IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
IB-MECA
5'-N-METHYLCARBOXAMIDOADENOSINE
2-CL-IB-MECA,Cl-IB-MECA, 2-Chloro-N6-(3-iodobenzyl)-adenosine-5μ-N-methyluronamide
5'-AMINOADENOSINE
(S)-(-)-TETRAHYDROFURAN-2-CARBOXYLIC ACID AMIDE
adenosine 5'-carboxamide
1-[6-[[(4-AMINO-3-IODOPHENYL)METHYL]AMINO]-9H-PURIN-9-YL]-1-DEOXY-N-METHYL-BETA-D-RIBOFURANURONAMIDE
(S)-(+)-Tetrahydrofurfurylamine
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