Hydroxy-PEG3-Mes
- CAS NO.:139115-89-2
- Empirical Formula: C7H16O6S
- Molecular Weight: 228.26
- MDL number: MFCD22574814
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:54:57
What is Hydroxy-PEG3-Mes?
Biological Activity
Hydroxy-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Properties of Hydroxy-PEG3-Mes
Boiling point: | 398.2±27.0 °C(Predicted) |
Density | 1.256±0.06 g/cm3(Predicted) |
pka | 14.36±0.10(Predicted) |
form | Liquid |
color | Colorless to light yellow |
Safety information for Hydroxy-PEG3-Mes
Computed Descriptors for Hydroxy-PEG3-Mes
New Products
(2S,4R)-4-amino-2-methyl-5-phenylpentanoic acid hydrochloride Tubulysin G Tubulysin M 2,2-diethoxyethanethioamide 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) Isoxazole, 3-[[[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl]thio]-4,5-dihydro-5,5-dimethyl- tetrahydro-4-methyl-2H-pyran 3-N-BOC-(S)-AMINO BUTYRONITRILE 3-Aminocyclobutanone hydrochloride 4,4-DIFLUOROCYCLOHEXANAMINE 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Imeglimin Hydrochloride IH Calcium Sodium Phosphosilicate IH Latanoprostene Bunod Lubiprostone Magnesium Trisilicate Flame Retardant Zinc Borate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate methyl 3-fluoro-4- thiomorpholino phenylcarbamate 7-Methoxyquinoline-4-carbonitrile 1H-Imidazole-4-carbonitrileRelated products of tetrahydrofuran
PEG14-t-butly ester
PEG8-t-butly ester
Hydroxy-PEG5-t-butyl acetate
Hydroxy-PEG7-t-butyl acetate
PEG4-acid
3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid
Hydroxy-PEG14-t-butly ester
Mes-PEG2-acid t-butyl ester
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