Hydroxy-PEG3-Mes
- CAS NO.：139115-89-2
- Empirical Formula: C7H16O6S
- Molecular Weight: 228.26
- MDL number: MFCD22574814
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:54:57
What is Hydroxy-PEG3-Mes?
Biological Activity
Hydroxy-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Properties of Hydroxy-PEG3-Mes
| Boiling point: | 398.2±27.0 °C(Predicted) |
| Density | 1.256±0.06 g/cm3(Predicted) |
| pka | 14.36±0.10(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
Safety information for Hydroxy-PEG3-Mes
Computed Descriptors for Hydroxy-PEG3-Mes
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
![3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid](https://img.chemicalbook.in/CAS/20150408/GIF/1334286-77-9.gif)
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