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HomeProduct name list3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid

3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid

  • CAS NO.:1334286-77-9
  • Empirical Formula: C7H14O5
  • Molecular Weight: 178.18
  • MDL number: MFCD20646030
  • Update Date: 2024-10-28 23:16:16
3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid Structural

What is 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid?

Description

Hydroxy-PEG2-acid sodium salt is a PEG linker containing a hydroxyl group with a terminal carboxylic acid (as sodium salt form). The free acid form is not stable due to the reaction of OH with PEG-COOH group to form polymer. The sodium salt form is stable for storage and shipping. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

Properties of 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid

Boiling point: 350.0±27.0 °C(Predicted)
Density  1.196±0.06 g/cm3(Predicted)
solubility  Soluble in Water, DMSO, DMF
pka 4.27±0.10(Predicted)
form  A liquid
color  Colorless to light yellow

Safety information for 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H318:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P310:Immediately call a POISON CENTER or doctor/physician.
P330:Rinse mouth.
P362:Take off contaminated clothing and wash before reuse.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.
P405:Store locked up.
P403+P233:Store in a well-ventilated place. Keep container tightly closed.
P501:Dispose of contents/container to..…

Computed Descriptors for 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid

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