Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listHYDROETHIDINE

HYDROETHIDINE

Synonym(s):2,7-Diamino-10-ethyl-9-phenyl-9,10-dihydrophenanthridine;2,7-Diamino-10-ethyl-9-phenyl-9,10-dihydrophenanthridine, DHE;3,8-Diamino-5,6-dihydro-5-ethyl-6-phenylphenanthridine;ActRIIB;Hydroethidine

  • CAS NO.:38483-26-0
  • Empirical Formula: C21H21N3
  • Molecular Weight: 315.41
  • MDL number: MFCD00077335
  • EINECS: 604-604-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
HYDROETHIDINE Structural

What is HYDROETHIDINE?

The Uses of HYDROETHIDINE

Dihydroethidium, also known as hydroethidine, is a dye that can permeate viable cells and accumulate in the nucleus after it is dehydrogenated to ethidium bromide and is used to measure oxygen reduction in phagocytes during respiratory burst. In the presence of an oxidant it will fluoresce and has been used as a dye in flow cytometry. Studies have used Dihydroethidium to study alveolar macrophages, blood leukocytes, and epithelial cells, among others, and has be used to measure intracellular H2O2 and O2-, and reactive oxygen. Dyes and metabolites.

General Description

A cell-permeable, chemically reduced ethidium derivative that can be used as a fluorogenic probe for the detection of reactive oxygen species (ROS). It undergoes significant oxidation in resting leukocytes, possibly through the uncoupling of mitochondrial oxidative phosphorylation. Cytosolic dihydroethidium displays blue fluorescence, however, following oxidation to ethidium and subsequent intercalation to DNA, a bright red fluorescence is achieved. Often used to determine the level of superoxide anion in cells by flow cytometry.

Biochem/physiol Actions

Cell permeable: yes

Properties of HYDROETHIDINE

Boiling point: 444.96°C (rough estimate)
Density  1.1227 (rough estimate)
refractive index  1.6380 (estimate)
storage temp.  −20°C
solubility  acetonitrile: soluble
CAS DataBase Reference 38483-26-0(CAS DataBase Reference)

Safety information for HYDROETHIDINE

Computed Descriptors for HYDROETHIDINE

Related products of tetrahydrofuran

You may like

  • Dihydroethidium CAS 38483-26-0
    Dihydroethidium CAS 38483-26-0
    38483-26-0
    View Details
  • Anti-Activin Receptor IIB antibody produced in goat CAS
    Anti-Activin Receptor IIB antibody produced in goat CAS
    View Details
  • 446292-08-6 (S)-2-{2-Oxo-3-[4-(3-oxo-morpholin-4-yl)-phenyl]-oxazolidin-5-ylmethyl}-isoindole-1,3-dione 99
    446292-08-6 (S)-2-{2-Oxo-3-[4-(3-oxo-morpholin-4-yl)-phenyl]-oxazolidin-5-ylmethyl}-isoindole-1,3-dione 99
    446292-08-6
    View Details
  • Iminostilbene 256-96-2 98
    Iminostilbene 256-96-2 98
    256-96-2
    View Details
  • 147403-52-9 > 99
    147403-52-9 > 99
    147403-52-9
    View Details
  • 5,6-Dimethoxy-2-(4-piperidinylmethyl)-1-indanone hydrochloride 120013-39-0 > 99.0
    5,6-Dimethoxy-2-(4-piperidinylmethyl)-1-indanone hydrochloride 120013-39-0 > 99.0
    120013-39-0
    View Details
  • 718635-93-9 3-(dimethylamino)-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one >99%
    718635-93-9 3-(dimethylamino)-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one >99%
    718635-93-9
    View Details
  • 147403-65-4 > 99
    147403-65-4 > 99
    147403-65-4
    View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.