HO-PEG-NH2

Synonym(s):Aminopolyethylene glycol;Aminopolyethylene glycol 10,000;Aminopolyethylene glycol 5,000

CAS NO.：32130-27-1
Empirical Formula: C6H15NO3
Molecular Weight: 149.1882
MDL number: MFCD00286223
SAFETY DATA SHEET (SDS)
Update Date: 2024-03-28 13:39:29

What is HO-PEG-NH2?

Description

m-PEG48-amine is a aqueous soluble PEG linker containing an amino group.it can react with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.

The Uses of HO-PEG-NH2

Reactant for:• ;Preparation of pH responsive self-healing hydrogels formed by boronate-catechol complexation1• ;Preparation of core-clickable PEG-branch-azide bivalent-bottle-brush polymers by ROMP2• ;Preparation of drug-loaded bivalent-bottle-brush polymers by graft-through ROMP3

The Uses of HO-PEG-NH2

O-(2-Aminoethyl)polyethylene glycol (PEG-NH₂) can be used:

As a capping ligand in the synthesis of water-dispersible and non-toxic nanocrystals (ZnS:Mn) for the development of environment friendly materials.
In the surface modification of magnetic nanoparticles (MNPs) for a variety of biomedical applications.

The Uses of HO-PEG-NH2

O-(2-Aminoethyl)polyethylene glycol has been used to synthesize PEG-poly(D,L-lactide-co-glycolide) (PEG-PLGA) conjugate for use in the synthesis of PLGA-based nanoparticles.

General Description

O-(2-Aminoethyl)polyethylene glycol is a heterobifunctional polyethylene glycol (hydroxyl-PEG-amine) useful in conjugation and crosslinking reactions.

Properties of HO-PEG-NH2

refractive index	1.474
Flash point:	278 °C
storage temp.	-20°C
form	solid or viscous liquid
Specific Gravity	1.15

Safety information for HO-PEG-NH2

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.