HEMICHOLINIUM-3
- CAS NO.:312-45-8
- Empirical Formula: C24H34N2O4.2Br
- Molecular Weight: 574.351
- MDL number: MFCD00011978
- EINECS: 206-227-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:15:32
What is HEMICHOLINIUM-3?
The Uses of HEMICHOLINIUM-3
Hemicholinium-3 has been used in the preparation of Krebs-HC-3 buffer to study its effects on choline uptake and choline acetyltransferase activity in differentiated human neuroblastoma (SK-N-SH) cells.
The Uses of HEMICHOLINIUM-3
Acetylcholine stores depletor
The Uses of HEMICHOLINIUM-3
Research tool as cholinergic probe, to deplete acetylcholine stores.
Biochem/physiol Actions
Hemicholinium-3 plays a role in blocking the neuronal choline uptake thereby inhibiting acetylcholine synthesis in the brain.
Properties of HEMICHOLINIUM-3
Melting point: | 180°; mp 226- 228° (dec) |
storage temp. | Store at -20°C |
solubility | ethanol: 1.3 mg/mL |
form | solid |
color | white |
Water Solubility | Water : 33.33 mg/mL (58.03 mM; Need ultrasonic) |
Merck | 13,4660 |
BRN | 5704458 |
EPA Substance Registry System | Morpholinium, 2,2'-[1,1'-biphenyl]-4,4'-diylbis[2-hydroxy-4,4-dimethyl-, dibromide (312-45-8) |
Safety information for HEMICHOLINIUM-3
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for HEMICHOLINIUM-3
New Products
4-Fluorophenylacetic acid 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate (6-METHYL-[1,3]DITHIOLO[4,5-b]QUINOXALIN-2-ONE INDAZOLE-3-CARBOXYLIC ACID 4-IODO BENZOIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5,6-Dimethoxyindanone 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
(4'-METHYLBIPHENYL-4-YL)-METHANOL
Hemicholinium
DL-ALPHA-(METHYLAMINOMETHYL)BENZYL ALCOHOL
1-(4-Methylphenyl)ethanol
2-amino-1-(4-methylphenyl)ethanol
HEMICHOLINIUM-3
4,4'-Dimethylbiphenyl
DIMETHYL DIETHYL AMMONIUM BROMIDE
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