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HomeProduct name listHARMANE-1,2,3,4-TETRAHYDRO-3-CARBOXYLIC ACID

HARMANE-1,2,3,4-TETRAHYDRO-3-CARBOXYLIC ACID

Synonym(s):1,2,3,4-Tetrahydroharmane-3-carboxylic acid;1-Methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid;1-Methyl-1,2,3,4-Tetrahydropyrido[3,4-b]indole-3-carboxylic acid;NSC 26225

HARMANE-1,2,3,4-TETRAHYDRO-3-CARBOXYLIC ACID Structural

What is HARMANE-1,2,3,4-TETRAHYDRO-3-CARBOXYLIC ACID?

The Uses of HARMANE-1,2,3,4-TETRAHYDRO-3-CARBOXYLIC ACID

Reactant involved in synthesis of molecules for biological studies including:• ;Cytotoxicity and insecticidal activities of harmine derivatives1• ;Isoquinolines, β-carbolines, and 3-deazapurines via oxidative decarboxylation2• ;Cytotoxic evaluation of 1,3-di- and 1,3,9-trisubstituted β-carbolines3

The Uses of HARMANE-1,2,3,4-TETRAHYDRO-3-CARBOXYLIC ACID

Reactant involved in synthesis of molecules for biological studies including:

  • Cytotoxicity and insecticidal activities of harmine derivatives
  • Isoquinolines, β-carbolines, and 3-deazapurines via oxidative decarboxylation
  • Cytotoxic evaluation of 1,3-di- and 1,3,9-trisubstituted β-carbolines

Definition

ChEBI: (1xi,3xi)-1,2,3,4-Tetrahydro-1-methyl-beta-carboline-3-carboxylic acid is a harmala alkaloid.

General Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Properties of HARMANE-1,2,3,4-TETRAHYDRO-3-CARBOXYLIC ACID

Melting point: 242-243 °C (decomp)
Boiling point: 488.0±45.0 °C(Predicted)
Density  1.301±0.06 g/cm3(Predicted)
storage temp.  −20°C
solubility  Methanol (Slightly, Heated)
form  Solid
pka 2.29±0.40(Predicted)
color  White to Off-White
CAS DataBase Reference 5470-37-1(CAS DataBase Reference)

Safety information for HARMANE-1,2,3,4-TETRAHYDRO-3-CARBOXYLIC ACID

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H317:Sensitisation, Skin
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for HARMANE-1,2,3,4-TETRAHYDRO-3-CARBOXYLIC ACID

InChIKey ZUPHXNBLQCSEIA-UHFFFAOYSA-N

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