hamaudol
- CAS NO.：735-46-6
- Empirical Formula: C15H16O5
- Molecular Weight: 276.28
- MDL number: MFCD32220467
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-16 15:32:52
What is hamaudol?
Definition
ChEBI: Hamaudol is a member of chromenes.
Biological Activity
Hamaudol is a chromone isolated from Saposhnikovia divaricata. It has obvious inhibitory ability on the activities of cyclooxygenase (COX)-1 and COX-2 with IC50 values of 0.30 and 0.57 mM, respectively, and has potent analgesic and anti-inflammatory effects.
in vivo
Hamaudol (Compound 7) increases the potency to exhibit a potent analgesia at doses of 1, 5 and 10 mg/kg in mice, although it do not show clear dose dependency.
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Properties of hamaudol
| Melting point: | 197.0-197.5 °C |
| Boiling point: | 464.7±45.0 °C(Predicted) |
| Density | 1.336±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Solid |
| pka | 6.77±0.70(Predicted) |
| color | White to off-white |
Safety information for hamaudol
Computed Descriptors for hamaudol
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Diclofenac Potassium Ornidazole IP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Aceclofenac IP/BP/EP Nimesulide BP SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION Methylcobalamin (vitamin B12) SODIUM METHYL PARABEN SODIUM VALPROATE Racecadotril XANTHAN GUMRelated products of tetrahydrofuran
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