hamaudol
- CAS NO.：735-46-6
- Empirical Formula: C15H16O5
- Molecular Weight: 276.28
- MDL number: MFCD32220467
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is hamaudol?
Definition
ChEBI: Hamaudol is a member of chromenes.
Biological Activity
Hamaudol is a chromone isolated from Saposhnikovia divaricata. It has obvious inhibitory ability on the activities of cyclooxygenase (COX)-1 and COX-2 with IC50 values of 0.30 and 0.57 mM, respectively, and has potent analgesic and anti-inflammatory effects.
in vivo
Hamaudol (Compound 7) increases the potency to exhibit a potent analgesia at doses of 1, 5 and 10 mg/kg in mice, although it do not show clear dose dependency.
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Properties of hamaudol
| Melting point: | 197.0-197.5 °C |
| Boiling point: | 464.7±45.0 °C(Predicted) |
| Density | 1.336±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Solid |
| pka | 6.77±0.70(Predicted) |
| color | White to off-white |
Safety information for hamaudol
Computed Descriptors for hamaudol
New Products
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