H-GLY-PRO-ARG-PRO-NH2
Synonym(s):Glycine-Proline-Arginine-Proline amide;Glycyl-L-prolyl-L-arginyl-L-prolinamide;GPRP amide
- CAS NO.:126047-75-4
- Empirical Formula: C18H32N8O4
- Molecular Weight: 424.5
- MDL number: MFCD00237962
- SAFETY DATA SHEET (SDS)
What is H-GLY-PRO-ARG-PRO-NH2?
The Uses of H-GLY-PRO-ARG-PRO-NH2
Gly-Pro-Arg-Pro amide has been used-
- as a constituent of buffer during fluid-phase and bound thrombin inhibition assays, to determine the activity of thrombin
- for blocking fibrin polymerization and preventing fibrin clot formation in presence of α-thrombin, in blood obtained from mice
- during preparation of human soluble fibrin, to block the polymerization of soluble fibrin
General Description
Gly-Pro-Arg-Pro is a peptide that mimics the N-terminal Gly-Pro-Arg region in the a chain of fibrin protein.
Biochem/physiol Actions
Gly-Pro-Arg-Pro peptide suppresses the early steps of fibrin polymerization. The amide derivative of this peptide prevents the degradation of fibrinogen and fragment D by plasmin, even in the presence of EGTA (ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid).
Properties of H-GLY-PRO-ARG-PRO-NH2
storage temp. | -20°C |
Safety information for H-GLY-PRO-ARG-PRO-NH2
Computed Descriptors for H-GLY-PRO-ARG-PRO-NH2
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
H-GLY-PRO-ARG-PRO-NH2
PEPTIDE II OF T WAGLERI VENOM
H-TYR-GLU-LYS-PRO-GLY-SER-PRO-PRO-ARG-GLU-VAL-VAL-PRO-ARG-PRO-ARG-GLY-VAL-OH
PR-11
AC-PRO-TYR-ASN-SER-SER-PRO-ARG-PRO-GLU-GLN-HIS-LYS-SER-TYR-LYS-CYS
PYROGLU-LEU-PRO-PRO-ARG-PRO-LYS-ILE-PRO-PRO
AAVHSSEEDLRTPPRPVSS
H-GLY-PRO-ARG-PRO-PRO-GLU-ARG-HIS-GLN-SER-NH2
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