H-GLY-PRO-ARG-PRO-NH2
Synonym(s):Glycine-Proline-Arginine-Proline amide;Glycyl-L-prolyl-L-arginyl-L-prolinamide;GPRP amide
- CAS NO.:126047-75-4
- Empirical Formula: C18H32N8O4
- Molecular Weight: 424.5
- MDL number: MFCD00237962
- SAFETY DATA SHEET (SDS)
What is H-GLY-PRO-ARG-PRO-NH2?
The Uses of H-GLY-PRO-ARG-PRO-NH2
Gly-Pro-Arg-Pro amide has been used-
- as a constituent of buffer during fluid-phase and bound thrombin inhibition assays, to determine the activity of thrombin
- for blocking fibrin polymerization and preventing fibrin clot formation in presence of α-thrombin, in blood obtained from mice
- during preparation of human soluble fibrin, to block the polymerization of soluble fibrin
General Description
Gly-Pro-Arg-Pro is a peptide that mimics the N-terminal Gly-Pro-Arg region in the a chain of fibrin protein.
Biochem/physiol Actions
Gly-Pro-Arg-Pro peptide suppresses the early steps of fibrin polymerization. The amide derivative of this peptide prevents the degradation of fibrinogen and fragment D by plasmin, even in the presence of EGTA (ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid).
Properties of H-GLY-PRO-ARG-PRO-NH2
storage temp. | -20°C |
Safety information for H-GLY-PRO-ARG-PRO-NH2
Computed Descriptors for H-GLY-PRO-ARG-PRO-NH2
New Products
ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
H-GLY-PRO-ARG-PRO-NH2
PEPTIDE II OF T WAGLERI VENOM
H-TYR-GLU-LYS-PRO-GLY-SER-PRO-PRO-ARG-GLU-VAL-VAL-PRO-ARG-PRO-ARG-GLY-VAL-OH
PR-11
AC-PRO-TYR-ASN-SER-SER-PRO-ARG-PRO-GLU-GLN-HIS-LYS-SER-TYR-LYS-CYS
PYROGLU-LEU-PRO-PRO-ARG-PRO-LYS-ILE-PRO-PRO
AAVHSSEEDLRTPPRPVSS
H-GLY-PRO-ARG-PRO-PRO-GLU-ARG-HIS-GLN-SER-NH2
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