H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT
- CAS NO.：23815-89-6
- Empirical Formula: C27H40N8O6
- Molecular Weight: 572.66
- MDL number: MFCD00076260
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT?
The Uses of H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT
Biologically active fragment of bradykinin
Biochem/physiol Actions
The bradykinin (BK) fragment (1-5) (RPPGF) is among the most stable of naturally occurring metabolites. It may be used as a marker for BK production in vivo. It is known that an intact Arg residue in the C-terminus is required for biological activities. BK 1-5 is the minimal peptide that inhibited α-thrombin-induced platelet aggregation and secretion and calcium mobilization. It also prevented α-thrombin from cleaving the thrombin receptor peptide, NATLDPRSFLLR, between arginine and serine. Such antithrombin activities of BK 1-5 may contribute to the cardioprotective nature of kinins.
Properties of H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT
| Density | 1.46±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO |
| pka | 3.50±0.10(Predicted) |
| form | Solid |
| color | White to off-white |
Safety information for H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT
Computed Descriptors for H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT
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