Glyphosine

Description

Glyphosine was introduced in 1973 and is preferably used in sugar beets. The synthesis starting with glycine uses two equivalents of formaldehyde and of phosphorous trichloride under oxidative conditions. A second derivative of Glyphosate is a cyclic phosphaoxazole being formed from Glyphosate and formaldehyde. This compound is claimed to control the growth of some grasses without dis- coloration or phytotoxicity.

The Uses of Glyphosine

Application: Complexing agent; pK-values: pK1: ·2, pK2: 2.0, pK3: 5.20, pK4: 6.77, pK5: 10.89

Anti-diabetic; delay onset of diabetes in non-obese NOD mice

Glyphosine binds to a pocket of MHC class II molecules I-Ag7 and DQ8, and modify T cell responses to the autoantigenic insulin B chain fragment 9–23 (B:9–23) peptide. Glyphosine stimulate IL-10 production and delay onset of diabetes in non-obese NOD mice.

The Uses of Glyphosine

Chemical ripener; plant growth regulator.

What are the applications of Application

N,N-Bis(phosphonomethyl)glycine is A complexing agent

Definition

ChEBI: A tertiary amino compound that consists of glycine bearing two N-phosphonomethyl substituents.

General Description

N,N-Bis(phosphonomethyl)glycine was present in the ligand bound to human apotransferrin.

Biochem/physiol Actions

Anti-diabetic; delay onset of diabetes in non-obese NOD mice