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HomeProduct name listGly-Gly-Leu

Gly-Gly-Leu

Gly-Gly-Leu Structural

What is Gly-Gly-Leu?

Chemical properties

White crystalline powder

The Uses of Gly-Gly-Leu

Gly-gly-leu is an oligopeptide, and also functions as a plant growth regulator.

Definition

ChEBI: Gly-Gly-Leu is a tripeptide composed of glycine, glycine and L-leucine residues joined in sequence. It has a role as a metabolite.

Synthesis

Glycylglycyl-L-leucine was prepared in 98% yield by hydrogenolysis of the protected tripeptide and crystallization of the product from aqueous ethanol. This matarial had [α]24D -28.4° (c, 2 in water), reported [α]20D -28. l° (c, 2.53 in water), [α]26D -28.0°, and [α]19D -29.9° (c, 2 in water)[1].

References

[1] Beechham A, et al. Residue rotations of L-leucine in the Di-, Tri-, Tetra-, and Penta-peptides of L-leucine and Glycine containing one L-leucyl residue. Australian Journal of Chemistry, 1967; 20: 1983 - 1989.

Properties of Gly-Gly-Leu

Melting point: 195-198 °C (decomp)
Boiling point: 573.7±45.0 °C(Predicted)
Density  1.199±0.06 g/cm3(Predicted)
storage temp.  −20°C
pka 3.35±0.10(Predicted)
InChI InChI=1S/C10H19N3O4/c1-6(2)3-7(10(16)17)13-9(15)5-12-8(14)4-11/h6-7H,3-5,11H2,1-2H3,(H,12,14)(H,13,15)(H,16,17)/t7-/m0/s1
CAS DataBase Reference 14857-82-0(CAS DataBase Reference)

Safety information for Gly-Gly-Leu

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H317:Sensitisation, Skin
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Gly-Gly-Leu

InChIKey XPJBQTCXPJNIFE-ZETCQYMHSA-N
SMILES C(O)(=O)[C@H](CC(C)C)NC(=O)CNC(=O)CN

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