GLYCOPROTEIN, ALPHA1-ACID HUMAN
Synonym(s):PSK;PSK1;TAO1;TAO2;α?-Acid Glycoprotein, Human Plasma
- CAS NO.：66455-27-4
- Empirical Formula: NULL
- Molecular Weight: 0
- MDL number: MFCD00131224
- Update Date: 2023-04-23 13:52:06
What is GLYCOPROTEIN, ALPHA1-ACID HUMAN?
The Uses of GLYCOPROTEIN, ALPHA1-ACID HUMAN
GLYCOPROTEIN, ALPHA1-ACID HUMAN was used to study nonviral gene delivery to the lung with copolymer-protected and transferrin-modified polyethylenimine.
The Uses of GLYCOPROTEIN, ALPHA1-ACID HUMAN
α1-Acid glycoprotein from human plasma has been used:
- as negatively charged protein to investigate the adsorption processes onto the surface of polyelectrolyte multilayers
- to incubate plates coated with purified antiserum in the study to investigate its serum concentration by ELISA
- to study the effect of its different concentrations on the antiviral activity of human immunodeficiency virus (HIV) protease inhibitors
General Description
α-1-Acid glycoprotein (AGP)/orosomucoid (ORM), a glycoprotein has a molecular weight of 41-43kDa. It is considered as one of the important acute phase proteins in humans and rats. AGP may belong to the lipocalin family.
Biochem/physiol Actions
α1-Acid glycoprotein possesses immunomodulating effects. It has the ability to bind to acidic drugs, like phenobarbital.
Purification Methods
Purify the glycoprotein 1 acid by passage through a carboxymethyl cellulose column, then through a Sephadex G-25 column. [Aronson et al. J Biol Chem 243 4564 1968.]
Properties of GLYCOPROTEIN, ALPHA1-ACID HUMAN
| storage temp. | 2-8°C |
| solubility | H2O: 10 mg/mL, clear, colorless |
| form | Lyophilized |
| Merck | 13,8018 |
Safety information for GLYCOPROTEIN, ALPHA1-ACID HUMAN
Computed Descriptors for GLYCOPROTEIN, ALPHA1-ACID HUMAN
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