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HomeProduct name listGLUTAMINASE

GLUTAMINASE

Synonym(s):L-Glutamine amidohydrolase

What is GLUTAMINASE?

The Uses of GLUTAMINASE

Glutaminase from E.coli has been used:

  • for the determination of glutamine from the cerebral cortex tissue extract
  • for immobilization on aminopropylsilylated controlled pore glass (CPG) for determination of glutamine
  • in combination with acivicin in in vitro melanoma cells and MCF-7 and OAW-42 cells for cell proliferation and invasiveness assay.

General Description

Glutaminase is an amidohydrolase. It has the catalytic domain in the N-terminal and the C-terminal extension possesses STAS domain.

Biochem/physiol Actions

Glutaminase from Escherichia coli along with acivicin, a glutamine analog regulates proliferation and invasiveness of cancer cells. Bacterial glutaminase is implicated in increasing the life span of cancer patients by lowering the tumor burden.

Properties of GLUTAMINASE

storage temp.  -20°C
form  lyophilized powder
color  Off-white to light yellow

Safety information for GLUTAMINASE

Computed Descriptors for GLUTAMINASE

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