GLIOVIRIN
- CAS NO.：83912-90-7
- Empirical Formula: C20H20N2O8S2
- Molecular Weight: 480.51
- MDL number: MFCD08274579
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:03:00
What is GLIOVIRIN?
Description
Gliovirin is a fungal metabolite that has been found in T. harzianum and has fungicidal, antimicrobial and anti-inflammatory activities. It is active against the plant pathogenic fungus P. ultimum (MIC = 60 ng/ml) and the parasite T. brucei brucei (IC50 = 90 ng/ml), but has no effect on the plant pathogenic fungi R. solani, P. omnivorum, T. basicola, R. arrhizus, and V. dahliae or the bacteria B. thuringiensis, P. fluorescens, and X. malvacearum when used at concentrations up to 1,000 ng/ml. Gliovirin decreases phorbol 12-myristate 13-acetate (TPA)- and ionomycin-induced increased expression of COX-2 (IC50 = 1 μM) and protein levels of IL-2 in Jurkat cells (IC50 = 5.2 μM).
Properties of GLIOVIRIN
| storage temp. | Store at -20°C |
| solubility | DMSO: soluble,Ethanol: soluble,Methanol: soluble |
| form | A solid |
Safety information for GLIOVIRIN
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P271:Use only outdoors or in a well-ventilated area. |
Computed Descriptors for GLIOVIRIN
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